The role of xerostomia in burning mouth syndrome: a case-control study

Objective : To assess the efficacy of anti-xerostomic topical medication (urea 10%) in patients with burning mouth syndrome (BMS). Method : Thirty-eight subjects diagnosed with BMS according to the International Association for the Study of Pain guidelines were randomized to either placebo (5% sodium carboxymethylcellulose, 0.15% methyl paraben, and 10% glycerol in distilled water qsp 100 g) or treatment (urea 10%) to be applied to the oral cavity 3-4 times per day for 3 months. The patients were evaluated before and after treatment with the following instruments: the EDOF-HC protocol (Orofacial Pain Clinic – Hospital das Clínicas), a xerostomia questionnaire, and quantitative sensory testing. Results : There were no differences in salivary flow or gustative, olfactory, or sensory thresholds (P>0.05). Fifteen (60%) patients reported improvement with the treatments (P=0.336). Conclusion : In conclusion, there were no differences between groups, and both exhibited an association between reported improvement and salivation.

Bibliographic Details

Main Authors:	Silva,Luciana Alvarenga da, Siqueira,José Tadeu Tesseroli de, Teixeira,Manoel Jacobsen, Siqueira,Silvia Regina Dowgan Tesseroli de
Format:	Digital revista
Language:	English
Published:	Academia Brasileira de Neurologia - ABNEURO 2014
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000200091
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