Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies
Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies.
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Academia Brasileira de Neurologia - ABNEURO
2013
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oai:scielo:S0004-282X20130013009202013-12-13Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsiesBaldissin,Mauricio MartinsSouza,Edna Marina de refractory epilepsies magnetic resonance texture analysis Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.71 n.12 20132013-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300920en10.1590/0004-282X20130219 |
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Baldissin,Mauricio Martins Souza,Edna Marina de |
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Baldissin,Mauricio Martins Souza,Edna Marina de Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
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Baldissin,Mauricio Martins Souza,Edna Marina de |
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Baldissin,Mauricio Martins |
title |
Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
title_short |
Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
title_full |
Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
title_fullStr |
Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
title_full_unstemmed |
Investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
title_sort |
investigation of magnetic resonance imaging texture analysis as an aid tool for characterization of refractory epilepsies |
description |
Refractory epilepsies are syndromes for which therapies that employ two or more antiepileptic drugs, separately or in association, do not result in control of crisis. Patients may present focal cortical dysplasia or diffuse dysplasia and/or hippocampal atrophic alterations that may not be detectable by a simple visual analysis in magnetic resonance imaging. The aim of this study was to evaluate MRI texture in regions of interest located in the hippocampi, limbic association cortex and prefrontal cortex of 20 patients with refractory epilepsy and to compare them with the same areas in 20 healthy individuals, in order to find out if the texture parameters could be related to the presence of the disease. Of the 11 texture parameters calculated, three indicated the existence of statistically significant differences between the studied groups. Such findings suggest the possibility of this technique contributing to studies of refractory epilepsies. |
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Academia Brasileira de Neurologia - ABNEURO |
publishDate |
2013 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013001300920 |
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AT baldissinmauriciomartins investigationofmagneticresonanceimagingtextureanalysisasanaidtoolforcharacterizationofrefractoryepilepsies AT souzaednamarinade investigationofmagneticresonanceimagingtextureanalysisasanaidtoolforcharacterizationofrefractoryepilepsies |
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1756374608254074880 |