What should you know about limbic encephalitis?

What should you know about limbic encephalitis?

Autoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition. It used to be regarded as a rare disease, usually paraneoplastic and with poor prognosis. However, with the recent recognition of membrane-surface directed antibodies, it is now known that in a substantial proportion of cases there is no association with any malignancy and there is a good prognosis if treated. Hence, early recognition and prompt initiation of immunotherapies are of great importance.

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Main Authors: Machado,Sara, Pinto,Amélia Nogueira, Irani,Sarosh R.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2012
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012
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spelling oai:scielo:S0004-282X20120010000122015-07-07What should you know about limbic encephalitis?Machado,SaraPinto,Amélia NogueiraIrani,Sarosh R. limbic autoimmune encephalitis encephalopathy intracellular antigens membrane surface antigens VGKC-complex LGI1 CASPR2 N-methylaspartate paraneoplastic syndrome immunotherapy Autoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition. It used to be regarded as a rare disease, usually paraneoplastic and with poor prognosis. However, with the recent recognition of membrane-surface directed antibodies, it is now known that in a substantial proportion of cases there is no association with any malignancy and there is a good prognosis if treated. Hence, early recognition and prompt initiation of immunotherapies are of great importance.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.70 n.10 20122012-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012en10.1590/S0004-282X2012001000012
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country Brasil
countrycode BR
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libraryname SciELO
language English
format Digital
author Machado,Sara
Pinto,Amélia Nogueira
Irani,Sarosh R.
spellingShingle Machado,Sara
Pinto,Amélia Nogueira
Irani,Sarosh R.
What should you know about limbic encephalitis?
author_facet Machado,Sara
Pinto,Amélia Nogueira
Irani,Sarosh R.
author_sort Machado,Sara
title What should you know about limbic encephalitis?
title_short What should you know about limbic encephalitis?
title_full What should you know about limbic encephalitis?
title_fullStr What should you know about limbic encephalitis?
title_full_unstemmed What should you know about limbic encephalitis?
title_sort what should you know about limbic encephalitis?
description Autoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition. It used to be regarded as a rare disease, usually paraneoplastic and with poor prognosis. However, with the recent recognition of membrane-surface directed antibodies, it is now known that in a substantial proportion of cases there is no association with any malignancy and there is a good prognosis if treated. Hence, early recognition and prompt initiation of immunotherapies are of great importance.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012
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