Depression in patients with refractory temporal lobe epilepsy
OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification of Diseases (ICD-10), and the Beck Depression Inventory. RESULTS: Seventeen of 25 patients (68%) had depressive disorder: 6 with dysthymia, three with major depressive episodes and 8 with recurrent depressive disorders. Two (8%) were diagnosed with mixed anxiety and depression. Only 5 of 17 patients (29.4%) were previously diagnosed with depressive disorder and received prior antidepressant treatment. Duration of epilepsy was significantly higher in patients with depressive disorder (p=0.016), but there was no relationship between depression and seizure frequency. CONCLUSION: This study confirmed that depressive disorders are common and underdiagnosed in patients with TLE refractory to AEDs. Patients with longer duration of epilepsy are at higher risk of having depression.
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Academia Brasileira de Neurologia - ABNEURO
2011
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oai:scielo:S0004-282X20110006000102011-10-27Depression in patients with refractory temporal lobe epilepsyGonçalves,Eleonora BorgesCendes,Fernando depressive disorders depression mesial temporal lobe epilepsy seizures OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification of Diseases (ICD-10), and the Beck Depression Inventory. RESULTS: Seventeen of 25 patients (68%) had depressive disorder: 6 with dysthymia, three with major depressive episodes and 8 with recurrent depressive disorders. Two (8%) were diagnosed with mixed anxiety and depression. Only 5 of 17 patients (29.4%) were previously diagnosed with depressive disorder and received prior antidepressant treatment. Duration of epilepsy was significantly higher in patients with depressive disorder (p=0.016), but there was no relationship between depression and seizure frequency. CONCLUSION: This study confirmed that depressive disorders are common and underdiagnosed in patients with TLE refractory to AEDs. Patients with longer duration of epilepsy are at higher risk of having depression.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.69 n.5 20112011-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600010en10.1590/S0004-282X2011000600010 |
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Gonçalves,Eleonora Borges Cendes,Fernando |
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Gonçalves,Eleonora Borges Cendes,Fernando Depression in patients with refractory temporal lobe epilepsy |
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Gonçalves,Eleonora Borges Cendes,Fernando |
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Gonçalves,Eleonora Borges |
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Depression in patients with refractory temporal lobe epilepsy |
title_short |
Depression in patients with refractory temporal lobe epilepsy |
title_full |
Depression in patients with refractory temporal lobe epilepsy |
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Depression in patients with refractory temporal lobe epilepsy |
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Depression in patients with refractory temporal lobe epilepsy |
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depression in patients with refractory temporal lobe epilepsy |
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OBJECTIVE: To evaluate the comorbidity of depressive disorders in patients with refractory temporal lobe epilepsy (TLE). METHOD: We evaluated 25 consecutive patients with refractory TLE (16 women and 9 men), using semi-structured psychiatric interviews, according to the International Classification of Diseases (ICD-10), and the Beck Depression Inventory. RESULTS: Seventeen of 25 patients (68%) had depressive disorder: 6 with dysthymia, three with major depressive episodes and 8 with recurrent depressive disorders. Two (8%) were diagnosed with mixed anxiety and depression. Only 5 of 17 patients (29.4%) were previously diagnosed with depressive disorder and received prior antidepressant treatment. Duration of epilepsy was significantly higher in patients with depressive disorder (p=0.016), but there was no relationship between depression and seizure frequency. CONCLUSION: This study confirmed that depressive disorders are common and underdiagnosed in patients with TLE refractory to AEDs. Patients with longer duration of epilepsy are at higher risk of having depression. |
publisher |
Academia Brasileira de Neurologia - ABNEURO |
publishDate |
2011 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000600010 |
work_keys_str_mv |
AT goncalveseleonoraborges depressioninpatientswithrefractorytemporallobeepilepsy AT cendesfernando depressioninpatientswithrefractorytemporallobeepilepsy |
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1756374527207538688 |