Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system
OBJECTIVE: To characterize neurological involvement in juvenile systemic lupus erythe-matosus. METHOD: The charts of all patients with the diagnosis of systemic lupus erythematosus before the age of 16 years, followed at the Rheumatology Unit of Pequeno Príncipe Hospital, from January 1992 to January 2006, were retrospectively reviewed, highlighting neuropsychiatric aspects. RESULTS: Forty-seven patients were included. Neuropsychiatric syndromes were found 29 (61.7%): seizures (17 / 36.2%), intractable headache (7 / 14.9%), mood disorders (5 / 10.6%), cerebrovascular disease (4 / 8.5%), acute confusional state (3 / 6.4%), aseptic meningitis (3 / 6.4%), psychosis (3 / 6.4%), chorea (3 / 6.4%), Guillain-Barré syndrome (2 / 4.3%) and cranial neuropathy (1 / 2.1%). Morbidity indexes (SLEDAI and SLICC) were higher among patients with neuropsychiatric manifestations (p<0.05). CONCLUSION: Neuropsychiatric syndromes are frequent, and add significant morbidity to juvenile systemic lupus erythematosus.
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia - ABNEURO
2007
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300013 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
oai:scielo:S0004-282X2007000300013 |
|---|---|
| record_format |
ojs |
| spelling |
oai:scielo:S0004-282X20070003000132007-07-24Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous systemSpinosa,Mônica JaquesBandeira,MárciaLiberalesso,Paulo Breno NoronhaVieira,Simone CarreiroJanz Jr,Loris LadySá,Eliane Gomes deLöhr Jr,Alfredo juvenile systemic lupus erythematosus neuropsychiatric syndromes OBJECTIVE: To characterize neurological involvement in juvenile systemic lupus erythe-matosus. METHOD: The charts of all patients with the diagnosis of systemic lupus erythematosus before the age of 16 years, followed at the Rheumatology Unit of Pequeno Príncipe Hospital, from January 1992 to January 2006, were retrospectively reviewed, highlighting neuropsychiatric aspects. RESULTS: Forty-seven patients were included. Neuropsychiatric syndromes were found 29 (61.7%): seizures (17 / 36.2%), intractable headache (7 / 14.9%), mood disorders (5 / 10.6%), cerebrovascular disease (4 / 8.5%), acute confusional state (3 / 6.4%), aseptic meningitis (3 / 6.4%), psychosis (3 / 6.4%), chorea (3 / 6.4%), Guillain-Barré syndrome (2 / 4.3%) and cranial neuropathy (1 / 2.1%). Morbidity indexes (SLEDAI and SLICC) were higher among patients with neuropsychiatric manifestations (p<0.05). CONCLUSION: Neuropsychiatric syndromes are frequent, and add significant morbidity to juvenile systemic lupus erythematosus.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.65 n.2b 20072007-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300013en10.1590/S0004-282X2007000300013 |
| institution |
SCIELO |
| collection |
OJS |
| country |
Brasil |
| countrycode |
BR |
| component |
Revista |
| access |
En linea |
| databasecode |
rev-scielo-br |
| tag |
revista |
| region |
America del Sur |
| libraryname |
SciELO |
| language |
English |
| format |
Digital |
| author |
Spinosa,Mônica Jaques Bandeira,Márcia Liberalesso,Paulo Breno Noronha Vieira,Simone Carreiro Janz Jr,Loris Lady Sá,Eliane Gomes de Löhr Jr,Alfredo |
| spellingShingle |
Spinosa,Mônica Jaques Bandeira,Márcia Liberalesso,Paulo Breno Noronha Vieira,Simone Carreiro Janz Jr,Loris Lady Sá,Eliane Gomes de Löhr Jr,Alfredo Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| author_facet |
Spinosa,Mônica Jaques Bandeira,Márcia Liberalesso,Paulo Breno Noronha Vieira,Simone Carreiro Janz Jr,Loris Lady Sá,Eliane Gomes de Löhr Jr,Alfredo |
| author_sort |
Spinosa,Mônica Jaques |
| title |
Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| title_short |
Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| title_full |
Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| title_fullStr |
Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| title_full_unstemmed |
Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| title_sort |
clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system |
| description |
OBJECTIVE: To characterize neurological involvement in juvenile systemic lupus erythe-matosus. METHOD: The charts of all patients with the diagnosis of systemic lupus erythematosus before the age of 16 years, followed at the Rheumatology Unit of Pequeno Príncipe Hospital, from January 1992 to January 2006, were retrospectively reviewed, highlighting neuropsychiatric aspects. RESULTS: Forty-seven patients were included. Neuropsychiatric syndromes were found 29 (61.7%): seizures (17 / 36.2%), intractable headache (7 / 14.9%), mood disorders (5 / 10.6%), cerebrovascular disease (4 / 8.5%), acute confusional state (3 / 6.4%), aseptic meningitis (3 / 6.4%), psychosis (3 / 6.4%), chorea (3 / 6.4%), Guillain-Barré syndrome (2 / 4.3%) and cranial neuropathy (1 / 2.1%). Morbidity indexes (SLEDAI and SLICC) were higher among patients with neuropsychiatric manifestations (p<0.05). CONCLUSION: Neuropsychiatric syndromes are frequent, and add significant morbidity to juvenile systemic lupus erythematosus. |
| publisher |
Academia Brasileira de Neurologia - ABNEURO |
| publishDate |
2007 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000300013 |
| work_keys_str_mv |
AT spinosamonicajaques clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT bandeiramarcia clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT liberalessopaulobrenonoronha clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT vieirasimonecarreiro clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT janzjrlorislady clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT saelianegomesde clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem AT lohrjralfredo clinicallaboratoryandneuroimagefindingsinjuvenilesystemiclupuserythematosuspresentinginvolvementofthenervoussystem |
| _version_ |
1756374371455205376 |