Kleine-Levin syndrome: interface between neurology and psychiatry

Kleine-Levin syndrome: interface between neurology and psychiatry

We report the first episode of Kleine-Levin (KLS) syndrome in a 17-year-old male. The illness onset, clinical features, neuropsychological evaluation and polysomnographic recording are described. Typical symptoms hypersomnia, hyperphagia and sexual disinhibition were observed besides behavioral disturbances, polysonographic and neuropsychological alterations. Behavioral disturbances similar to a manic episode including psychotic symptoms were relevant. The pharmacologic treatment included lithium, methylphenidate and risperidone. The introduction of risperidone aimed the control of psychotic symptoms and the persistent manifestations of hypersexuality after sleepness control and to the best of our knowledge there are no other report regarding risperidone use for KLS in the literature.

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Main Authors: Justo,Luís Pereira, Calil,Helena Maria, Prado-Bolognani,Sílvia A., Muszkat,Mauro
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100030
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spelling oai:scielo:S0004-282X20070001000302007-03-21Kleine-Levin syndrome: interface between neurology and psychiatryJusto,Luís PereiraCalil,Helena MariaPrado-Bolognani,Sílvia A.Muszkat,Mauro Kleine-Levin neuropsychology polysomnography risperidone sleep disorders We report the first episode of Kleine-Levin (KLS) syndrome in a 17-year-old male. The illness onset, clinical features, neuropsychological evaluation and polysomnographic recording are described. Typical symptoms hypersomnia, hyperphagia and sexual disinhibition were observed besides behavioral disturbances, polysonographic and neuropsychological alterations. Behavioral disturbances similar to a manic episode including psychotic symptoms were relevant. The pharmacologic treatment included lithium, methylphenidate and risperidone. The introduction of risperidone aimed the control of psychotic symptoms and the persistent manifestations of hypersexuality after sleepness control and to the best of our knowledge there are no other report regarding risperidone use for KLS in the literature.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.65 n.1 20072007-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100030en10.1590/S0004-282X2007000100030
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Justo,Luís Pereira
Calil,Helena Maria
Prado-Bolognani,Sílvia A.
Muszkat,Mauro
spellingShingle Justo,Luís Pereira
Calil,Helena Maria
Prado-Bolognani,Sílvia A.
Muszkat,Mauro
Kleine-Levin syndrome: interface between neurology and psychiatry
author_facet Justo,Luís Pereira
Calil,Helena Maria
Prado-Bolognani,Sílvia A.
Muszkat,Mauro
author_sort Justo,Luís Pereira
title Kleine-Levin syndrome: interface between neurology and psychiatry
title_short Kleine-Levin syndrome: interface between neurology and psychiatry
title_full Kleine-Levin syndrome: interface between neurology and psychiatry
title_fullStr Kleine-Levin syndrome: interface between neurology and psychiatry
title_full_unstemmed Kleine-Levin syndrome: interface between neurology and psychiatry
title_sort kleine-levin syndrome: interface between neurology and psychiatry
description We report the first episode of Kleine-Levin (KLS) syndrome in a 17-year-old male. The illness onset, clinical features, neuropsychological evaluation and polysomnographic recording are described. Typical symptoms hypersomnia, hyperphagia and sexual disinhibition were observed besides behavioral disturbances, polysonographic and neuropsychological alterations. Behavioral disturbances similar to a manic episode including psychotic symptoms were relevant. The pharmacologic treatment included lithium, methylphenidate and risperidone. The introduction of risperidone aimed the control of psychotic symptoms and the persistent manifestations of hypersexuality after sleepness control and to the best of our knowledge there are no other report regarding risperidone use for KLS in the literature.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100030
work_keys_str_mv AT justoluispereira kleinelevinsyndromeinterfacebetweenneurologyandpsychiatry
AT calilhelenamaria kleinelevinsyndromeinterfacebetweenneurologyandpsychiatry
AT pradobolognanisilviaa kleinelevinsyndromeinterfacebetweenneurologyandpsychiatry
AT muszkatmauro kleinelevinsyndromeinterfacebetweenneurologyandpsychiatry
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