Clonidine in respiratory panic disorder subtype
OBJECTIVE: Clonidine, which inhibits locus coeruleus discharge, would seem for theoretical reasons to be a good antipanic drug. Panic disorder (PD) presents a heterogeneous cluster of symptoms and a classification based on subtypes has been suggested and the respiratory symptoms group appears as a distinct subtype. METHOD: We report three cases of respiratory PD patients who were successfully treated with clonidine. RESULTS: Patients obtained panic free status, reduced anxiety levels and better functioning after clonidine administration (0.30-0.45 mg/day) for 6 weeks. CONCLUSION: Clonidine can be effective in the treatment of respiratory PD. This drug might play a role in relieving symptoms of anxiety due to noradrenergic hyperactivity in these patients.
Main Authors: | Valença,Alexandre M., Nardi,Antonio E., Mezzasalma,Marco A., Nascimento,Isabella, Lopes,Fabiana L., Zin,Walter A., Versiani,Marcio |
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Format: | Digital revista |
Language: | English |
Published: |
Academia Brasileira de Neurologia - ABNEURO
2004
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000300004 |
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