Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease

Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease

OBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. According to the clinical and laboratory data the diagnosis of adult's still Disease was established. The treatment was begun and few days after an initial improvement a sudden neurologic deterioration with coma and seizures has occurred. Hours later the patient died. Clinical, laboratorial, and pathologic data will be presented. CONCLUSION: To our knowledge this is the second description of a fatal disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease, but with a much more fulminating evolution than previously reported. Some etiopathogenic mechanisms could be shared in these two disorders explaining this coexistence.

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Main Authors: Domingues,Renan B., Gama,Ana Maria Casati da, Caser,Eliana B., Musso,Carlos, Santos,Maria Carmen S.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018
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spelling oai:scielo:S0004-282X20030002000182003-06-09Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still diseaseDomingues,Renan B.Gama,Ana Maria Casati daCaser,Eliana B.Musso,CarlosSantos,Maria Carmen S. adult's Still disease cerebral thrombotic microangiopathy thrombotic thrombocitopenic purpura OBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. According to the clinical and laboratory data the diagnosis of adult's still Disease was established. The treatment was begun and few days after an initial improvement a sudden neurologic deterioration with coma and seizures has occurred. Hours later the patient died. Clinical, laboratorial, and pathologic data will be presented. CONCLUSION: To our knowledge this is the second description of a fatal disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease, but with a much more fulminating evolution than previously reported. Some etiopathogenic mechanisms could be shared in these two disorders explaining this coexistence.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.61 n.2A 20032003-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018en10.1590/S0004-282X2003000200018
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Domingues,Renan B.
Gama,Ana Maria Casati da
Caser,Eliana B.
Musso,Carlos
Santos,Maria Carmen S.
spellingShingle Domingues,Renan B.
Gama,Ana Maria Casati da
Caser,Eliana B.
Musso,Carlos
Santos,Maria Carmen S.
Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
author_facet Domingues,Renan B.
Gama,Ana Maria Casati da
Caser,Eliana B.
Musso,Carlos
Santos,Maria Carmen S.
author_sort Domingues,Renan B.
title Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
title_short Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
title_full Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
title_fullStr Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
title_full_unstemmed Disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease
title_sort disseminated cerebral thrombotic microangiopathy in a patient with adult's still disease
description OBJECTIVE: The aim of this report is to describe a fatal disseminated thrombotic micoangiopathy with renal, pancreatic, and cerebral involvement in a patient with recently diagnosed adult's Still disease (ASD). CASE REPORT: A previously healthy 15 year old girl was admitted to our hospital. According to the clinical and laboratory data the diagnosis of adult's still Disease was established. The treatment was begun and few days after an initial improvement a sudden neurologic deterioration with coma and seizures has occurred. Hours later the patient died. Clinical, laboratorial, and pathologic data will be presented. CONCLUSION: To our knowledge this is the second description of a fatal disseminated cerebral thrombotic microangiopathy in a patient with adult's Still disease, but with a much more fulminating evolution than previously reported. Some etiopathogenic mechanisms could be shared in these two disorders explaining this coexistence.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000200018
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AT gamaanamariacasatida disseminatedcerebralthromboticmicroangiopathyinapatientwithadultsstilldisease
AT caserelianab disseminatedcerebralthromboticmicroangiopathyinapatientwithadultsstilldisease
AT mussocarlos disseminatedcerebralthromboticmicroangiopathyinapatientwithadultsstilldisease
AT santosmariacarmens disseminatedcerebralthromboticmicroangiopathyinapatientwithadultsstilldisease
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