Malignant transformation of pleomorphic xanthoastrocytoma: case report

We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.

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Main Authors: Tella Jr,Oswaldo Ignácio de, Herculano,Marco Antonio, Prandini,Mirto Nelso, Stavale,João Norberto, Aguiar,Paulo Henrique
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020
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spelling oai:scielo:S0004-282X20030001000202003-04-16Malignant transformation of pleomorphic xanthoastrocytoma: case reportTella Jr,Oswaldo Ignácio deHerculano,Marco AntonioPrandini,Mirto NelsoStavale,João NorbertoAguiar,Paulo Henrique xanthoastrocytoma astrocytoma tumor histopathology We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.61 n.1 20032003-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020en10.1590/S0004-282X2003000100020
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libraryname SciELO
language English
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author Tella Jr,Oswaldo Ignácio de
Herculano,Marco Antonio
Prandini,Mirto Nelso
Stavale,João Norberto
Aguiar,Paulo Henrique
spellingShingle Tella Jr,Oswaldo Ignácio de
Herculano,Marco Antonio
Prandini,Mirto Nelso
Stavale,João Norberto
Aguiar,Paulo Henrique
Malignant transformation of pleomorphic xanthoastrocytoma: case report
author_facet Tella Jr,Oswaldo Ignácio de
Herculano,Marco Antonio
Prandini,Mirto Nelso
Stavale,João Norberto
Aguiar,Paulo Henrique
author_sort Tella Jr,Oswaldo Ignácio de
title Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_short Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_full Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_fullStr Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_full_unstemmed Malignant transformation of pleomorphic xanthoastrocytoma: case report
title_sort malignant transformation of pleomorphic xanthoastrocytoma: case report
description We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which revealed a friable tumor, easily differentiated from the normal parenchyma, with cystic components. The histopathological examination demonstrated pleomorphic xanthoastrocytoma with malignant transformation. Histologically, the tumor at first procedure was composed of pleomorphic astrocytes with multinucleated and foamy cells. A rare case of malignant transformation in pleomorphic xanthoastrocytoma is presented, discussed and illustrated in this paper.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2003
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000100020
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AT prandinimirtonelso malignanttransformationofpleomorphicxanthoastrocytomacasereport
AT stavalejoaonorberto malignanttransformationofpleomorphicxanthoastrocytomacasereport
AT aguiarpaulohenrique malignanttransformationofpleomorphicxanthoastrocytomacasereport
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