Polymyositis: clinical investigation in two sisters
We present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image tests. In both cases, clinical manifestations started in childhood, without signs of involvement of the central and peripheral nervous system. Both patients proved to respond to a therapeutics based on corticosteroids. The degree of relatedness between their parents corroborate the notion that genetic factors may contribute to the development of the disease.
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Academia Brasileira de Neurologia - ABNEURO
2002
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oai:scielo:S0004-282X20020004000202002-09-10Polymyositis: clinical investigation in two sistersKarnikowski,Margô Gomes de OliveiraCosta,Bruno Rodrigues VelosoOsella,Oscar Francisco SanchezNóbrega,Otávio de Tolêdo polymyositis inflammatory myopathy We present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image tests. In both cases, clinical manifestations started in childhood, without signs of involvement of the central and peripheral nervous system. Both patients proved to respond to a therapeutics based on corticosteroids. The degree of relatedness between their parents corroborate the notion that genetic factors may contribute to the development of the disease.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.60 n.3A 20022002-09-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400020en10.1590/S0004-282X2002000400020 |
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Karnikowski,Margô Gomes de Oliveira Costa,Bruno Rodrigues Veloso Osella,Oscar Francisco Sanchez Nóbrega,Otávio de Tolêdo |
| spellingShingle |
Karnikowski,Margô Gomes de Oliveira Costa,Bruno Rodrigues Veloso Osella,Oscar Francisco Sanchez Nóbrega,Otávio de Tolêdo Polymyositis: clinical investigation in two sisters |
| author_facet |
Karnikowski,Margô Gomes de Oliveira Costa,Bruno Rodrigues Veloso Osella,Oscar Francisco Sanchez Nóbrega,Otávio de Tolêdo |
| author_sort |
Karnikowski,Margô Gomes de Oliveira |
| title |
Polymyositis: clinical investigation in two sisters |
| title_short |
Polymyositis: clinical investigation in two sisters |
| title_full |
Polymyositis: clinical investigation in two sisters |
| title_fullStr |
Polymyositis: clinical investigation in two sisters |
| title_full_unstemmed |
Polymyositis: clinical investigation in two sisters |
| title_sort |
polymyositis: clinical investigation in two sisters |
| description |
We present an investigation of a case of polymyositis affecting two sisters of one same parenthood. Their cases have been documented for almost two decades, being investigated by means of a diagnostic protocol which combined clinical findings as well as laboratorial, histopathological and image tests. In both cases, clinical manifestations started in childhood, without signs of involvement of the central and peripheral nervous system. Both patients proved to respond to a therapeutics based on corticosteroids. The degree of relatedness between their parents corroborate the notion that genetic factors may contribute to the development of the disease. |
| publisher |
Academia Brasileira de Neurologia - ABNEURO |
| publishDate |
2002 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2002000400020 |
| work_keys_str_mv |
AT karnikowskimargogomesdeoliveira polymyositisclinicalinvestigationintwosisters AT costabrunorodriguesveloso polymyositisclinicalinvestigationintwosisters AT osellaoscarfranciscosanchez polymyositisclinicalinvestigationintwosisters AT nobregaotaviodetoledo polymyositisclinicalinvestigationintwosisters |
| _version_ |
1756374211220209664 |