Pulmonary involvement in patients with HTLV-I associated myelopathy

Pulmonary involvement in HTLV-I patients has been identified by several authors in Africa, Japan and Brazil. The objective of this controlled study is to establish an association between HAM and lymphocytosis in the bronchoalveolar fluid (BAL). Thirty-five adult patients with non-traumatic and non-tumoral myelopathy filled out a detailed historical survey and underwent a neurological examination, a thoracic radiological evaluation and a CSF examination. Of the patients in this sample, 22 were diagnosed with HTLV-I associated myelopathy and 13 had myelopathies with other etiologies. Lymphocytosis in the BAL fluid was detected in 18 (82%) of the HAM patients and in 2 (15%) of non-HAM patients. We concluded that the lung represents an important organ in the pathogenesis of HAM.

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Main Authors: Mattos,Kilma, Melo,Ailton, Publio,Conceição Queiroz Leandro, Peçanha-Martins,Antonio Carlos, Freitas,Virgínia, Gomes,Irenio
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1995
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500009
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spelling oai:scielo:S0004-282X19950005000092010-12-08Pulmonary involvement in patients with HTLV-I associated myelopathyMattos,KilmaMelo,AiltonPublio,Conceição Queiroz LeandroPeçanha-Martins,Antonio CarlosFreitas,VirgíniaGomes,Irenio HTLV-I TSP encephalomyeloneuropathy myelopathy HTLV-I associated myelopathy (HAM) alveolitis Pulmonary involvement in HTLV-I patients has been identified by several authors in Africa, Japan and Brazil. The objective of this controlled study is to establish an association between HAM and lymphocytosis in the bronchoalveolar fluid (BAL). Thirty-five adult patients with non-traumatic and non-tumoral myelopathy filled out a detailed historical survey and underwent a neurological examination, a thoracic radiological evaluation and a CSF examination. Of the patients in this sample, 22 were diagnosed with HTLV-I associated myelopathy and 13 had myelopathies with other etiologies. Lymphocytosis in the BAL fluid was detected in 18 (82%) of the HAM patients and in 2 (15%) of non-HAM patients. We concluded that the lung represents an important organ in the pathogenesis of HAM.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.53 n.4 19951995-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500009en10.1590/S0004-282X1995000500009
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Mattos,Kilma
Melo,Ailton
Publio,Conceição Queiroz Leandro
Peçanha-Martins,Antonio Carlos
Freitas,Virgínia
Gomes,Irenio
spellingShingle Mattos,Kilma
Melo,Ailton
Publio,Conceição Queiroz Leandro
Peçanha-Martins,Antonio Carlos
Freitas,Virgínia
Gomes,Irenio
Pulmonary involvement in patients with HTLV-I associated myelopathy
author_facet Mattos,Kilma
Melo,Ailton
Publio,Conceição Queiroz Leandro
Peçanha-Martins,Antonio Carlos
Freitas,Virgínia
Gomes,Irenio
author_sort Mattos,Kilma
title Pulmonary involvement in patients with HTLV-I associated myelopathy
title_short Pulmonary involvement in patients with HTLV-I associated myelopathy
title_full Pulmonary involvement in patients with HTLV-I associated myelopathy
title_fullStr Pulmonary involvement in patients with HTLV-I associated myelopathy
title_full_unstemmed Pulmonary involvement in patients with HTLV-I associated myelopathy
title_sort pulmonary involvement in patients with htlv-i associated myelopathy
description Pulmonary involvement in HTLV-I patients has been identified by several authors in Africa, Japan and Brazil. The objective of this controlled study is to establish an association between HAM and lymphocytosis in the bronchoalveolar fluid (BAL). Thirty-five adult patients with non-traumatic and non-tumoral myelopathy filled out a detailed historical survey and underwent a neurological examination, a thoracic radiological evaluation and a CSF examination. Of the patients in this sample, 22 were diagnosed with HTLV-I associated myelopathy and 13 had myelopathies with other etiologies. Lymphocytosis in the BAL fluid was detected in 18 (82%) of the HAM patients and in 2 (15%) of non-HAM patients. We concluded that the lung represents an important organ in the pathogenesis of HAM.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 1995
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000500009
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AT pecanhamartinsantoniocarlos pulmonaryinvolvementinpatientswithhtlviassociatedmyelopathy
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