Simple and safe heparin regimen for acute ischaemia

Simple and safe heparin regimen for acute ischaemia

The risk/benefit ratio of acute anticoagulation in ischaemic cerebro-vascular disease is not clearly established. A simple and safe intermittent intravenous heparin regimen (20000 IU daily) was used prospectively in 50 patients of 57 ± 14 (m ± sd) years of age whose blood pressures ranged from normal to severe hypertension. Twenty-two patients had cardiogenic embolism and the remaining had recurrent severe transient ischaemic attacks of recent onset or progressive cerebral infarcts. Time of exposure to heparin was 6.4 ± 4 (m±sd) days. Two patients had recurrences of cerebral thromboembolism and none had bleeding complications. This is a safe and efficient method of anticoagulation for patients with cerebral ischaemia when continuous infusion of heparin or close monitoring of clotting times are not used routinely.

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Main Authors: Bittencourt,P. R. M., Padilha,S., Mazer,S.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 1986
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1986000100003
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spelling oai:scielo:S0004-282X19860001000032011-06-29Simple and safe heparin regimen for acute ischaemiaBittencourt,P. R. M.Padilha,S.Mazer,S.The risk/benefit ratio of acute anticoagulation in ischaemic cerebro-vascular disease is not clearly established. A simple and safe intermittent intravenous heparin regimen (20000 IU daily) was used prospectively in 50 patients of 57 ± 14 (m ± sd) years of age whose blood pressures ranged from normal to severe hypertension. Twenty-two patients had cardiogenic embolism and the remaining had recurrent severe transient ischaemic attacks of recent onset or progressive cerebral infarcts. Time of exposure to heparin was 6.4 ± 4 (m±sd) days. Two patients had recurrences of cerebral thromboembolism and none had bleeding complications. This is a safe and efficient method of anticoagulation for patients with cerebral ischaemia when continuous infusion of heparin or close monitoring of clotting times are not used routinely.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.44 n.1 19861986-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1986000100003en10.1590/S0004-282X1986000100003
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Bittencourt,P. R. M.
Padilha,S.
Mazer,S.
spellingShingle Bittencourt,P. R. M.
Padilha,S.
Mazer,S.
Simple and safe heparin regimen for acute ischaemia
author_facet Bittencourt,P. R. M.
Padilha,S.
Mazer,S.
author_sort Bittencourt,P. R. M.
title Simple and safe heparin regimen for acute ischaemia
title_short Simple and safe heparin regimen for acute ischaemia
title_full Simple and safe heparin regimen for acute ischaemia
title_fullStr Simple and safe heparin regimen for acute ischaemia
title_full_unstemmed Simple and safe heparin regimen for acute ischaemia
title_sort simple and safe heparin regimen for acute ischaemia
description The risk/benefit ratio of acute anticoagulation in ischaemic cerebro-vascular disease is not clearly established. A simple and safe intermittent intravenous heparin regimen (20000 IU daily) was used prospectively in 50 patients of 57 ± 14 (m ± sd) years of age whose blood pressures ranged from normal to severe hypertension. Twenty-two patients had cardiogenic embolism and the remaining had recurrent severe transient ischaemic attacks of recent onset or progressive cerebral infarcts. Time of exposure to heparin was 6.4 ± 4 (m±sd) days. Two patients had recurrences of cerebral thromboembolism and none had bleeding complications. This is a safe and efficient method of anticoagulation for patients with cerebral ischaemia when continuous infusion of heparin or close monitoring of clotting times are not used routinely.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 1986
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1986000100003
work_keys_str_mv AT bittencourtprm simpleandsafeheparinregimenforacuteischaemia
AT padilhas simpleandsafeheparinregimenforacuteischaemia
AT mazers simpleandsafeheparinregimenforacuteischaemia
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