Bilateral interstitial keratitis in a patient with presumed brain tuberculoma
ABSTRACT Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in the world. Tuberculosis is considered one of the causes of interstitial keratitis. Malnutrition and anemia are risk factors of the disseminated disease. This is a case report of a 10-year-old child who presented with decreased visual acuity and a clinical diagnosis of bilateral interstitial keratitis and sclero-uveitis. The patient had been treated with topical steroids with partial improvement. Examinations revealed severe iron deficiency anemia, negative serologies for human immunodeficiency virus and syphilis, positivity for cytomegalovirus- and herpes simplex-specific IgG, and purified protein derivative of 17 mm. During the follow-up, the patient presented with tonic-clonic seizures, and magnetic resonance imaging findings suggested a central nervous system tuberculoma. Interstitial keratitis improvement was observed after specific tuberculosis treatment. This is the first case report describing the association of interstitial keratitis and central nervous system tuberculoma.
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Conselho Brasileiro de Oftalmologia
2022
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oai:scielo:S0004-274920220050032132022-02-11Bilateral interstitial keratitis in a patient with presumed brain tuberculomaCosta,Elaine FiodOliveira,João Victor PimentelPinto,Luciano MoreiraAzevedo,Conceição de Maria Pedrozo e SilvaHofling-Lima,Ana Luisa Keratitis Scleritis Intracranial tuberculoma Ocular tuberculosis Anemia, iron deficiency Humans Case report ABSTRACT Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in the world. Tuberculosis is considered one of the causes of interstitial keratitis. Malnutrition and anemia are risk factors of the disseminated disease. This is a case report of a 10-year-old child who presented with decreased visual acuity and a clinical diagnosis of bilateral interstitial keratitis and sclero-uveitis. The patient had been treated with topical steroids with partial improvement. Examinations revealed severe iron deficiency anemia, negative serologies for human immunodeficiency virus and syphilis, positivity for cytomegalovirus- and herpes simplex-specific IgG, and purified protein derivative of 17 mm. During the follow-up, the patient presented with tonic-clonic seizures, and magnetic resonance imaging findings suggested a central nervous system tuberculoma. Interstitial keratitis improvement was observed after specific tuberculosis treatment. This is the first case report describing the association of interstitial keratitis and central nervous system tuberculoma.info:eu-repo/semantics/openAccessConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia n.ahead 20222022-01-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492022005003213en10.5935/0004-2749.20230015 |
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Costa,Elaine Fiod Oliveira,João Victor Pimentel Pinto,Luciano Moreira Azevedo,Conceição de Maria Pedrozo e Silva Hofling-Lima,Ana Luisa |
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Costa,Elaine Fiod Oliveira,João Victor Pimentel Pinto,Luciano Moreira Azevedo,Conceição de Maria Pedrozo e Silva Hofling-Lima,Ana Luisa Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
author_facet |
Costa,Elaine Fiod Oliveira,João Victor Pimentel Pinto,Luciano Moreira Azevedo,Conceição de Maria Pedrozo e Silva Hofling-Lima,Ana Luisa |
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Costa,Elaine Fiod |
title |
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
title_short |
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
title_full |
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
title_fullStr |
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
title_full_unstemmed |
Bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
title_sort |
bilateral interstitial keratitis in a patient with presumed brain tuberculoma |
description |
ABSTRACT Interstitial keratitis is an inflammation of the corneal stroma without epithelium or endothelium involvement. The underlying causes are mostly infectious or immune mediated. Brazil has one of the highest incidence rates of tuberculosis in the world. Tuberculosis is considered one of the causes of interstitial keratitis. Malnutrition and anemia are risk factors of the disseminated disease. This is a case report of a 10-year-old child who presented with decreased visual acuity and a clinical diagnosis of bilateral interstitial keratitis and sclero-uveitis. The patient had been treated with topical steroids with partial improvement. Examinations revealed severe iron deficiency anemia, negative serologies for human immunodeficiency virus and syphilis, positivity for cytomegalovirus- and herpes simplex-specific IgG, and purified protein derivative of 17 mm. During the follow-up, the patient presented with tonic-clonic seizures, and magnetic resonance imaging findings suggested a central nervous system tuberculoma. Interstitial keratitis improvement was observed after specific tuberculosis treatment. This is the first case report describing the association of interstitial keratitis and central nervous system tuberculoma. |
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Conselho Brasileiro de Oftalmologia |
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2022 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492022005003213 |
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