Amblyopia: neural basis and therapeutic approaches
ABSTRACT Abnormalities in visual processing caused by visual deprivation or abnormal binocular interaction may induce amblyopia, which is characterized by reduced visual acuity. Occlusion therapy, the conventional treatment, requires special attention as occlusion of the fellow normal eye may reduce its visual acuity and impair binocular vision. Besides recovering visual acuity, some researchers have recommended restoration of stereoacuity and motor fusion and reverse suppression in order to prevent diplopia. Recent studies have documented that the amblyopic visual cortex has a normal complement of cells but reduced spatial resolution and a disordered topographical map. Changes occurring in the late sensitive period selectively impact the parvocellular pathway. Distinct morphophysiologic and psychophysical deficits may demand individualization of therapy, which might provide greater and longer-lasting residual plasticity in some children.
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Conselho Brasileiro de Oftalmologia
2016
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oai:scielo:S0004-274920160005003462016-11-30Amblyopia: neural basis and therapeutic approachesBretas,Caio César PeixotoSoriano,Renato Nery Amblyopia Visual acuity Neural plasticity Visual córtex ABSTRACT Abnormalities in visual processing caused by visual deprivation or abnormal binocular interaction may induce amblyopia, which is characterized by reduced visual acuity. Occlusion therapy, the conventional treatment, requires special attention as occlusion of the fellow normal eye may reduce its visual acuity and impair binocular vision. Besides recovering visual acuity, some researchers have recommended restoration of stereoacuity and motor fusion and reverse suppression in order to prevent diplopia. Recent studies have documented that the amblyopic visual cortex has a normal complement of cells but reduced spatial resolution and a disordered topographical map. Changes occurring in the late sensitive period selectively impact the parvocellular pathway. Distinct morphophysiologic and psychophysical deficits may demand individualization of therapy, which might provide greater and longer-lasting residual plasticity in some children.info:eu-repo/semantics/openAccessConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia v.79 n.5 20162016-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500346en10.5935/0004-2749.20160099 |
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Bretas,Caio César Peixoto Soriano,Renato Nery |
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Bretas,Caio César Peixoto Soriano,Renato Nery Amblyopia: neural basis and therapeutic approaches |
| author_facet |
Bretas,Caio César Peixoto Soriano,Renato Nery |
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Bretas,Caio César Peixoto |
| title |
Amblyopia: neural basis and therapeutic approaches |
| title_short |
Amblyopia: neural basis and therapeutic approaches |
| title_full |
Amblyopia: neural basis and therapeutic approaches |
| title_fullStr |
Amblyopia: neural basis and therapeutic approaches |
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Amblyopia: neural basis and therapeutic approaches |
| title_sort |
amblyopia: neural basis and therapeutic approaches |
| description |
ABSTRACT Abnormalities in visual processing caused by visual deprivation or abnormal binocular interaction may induce amblyopia, which is characterized by reduced visual acuity. Occlusion therapy, the conventional treatment, requires special attention as occlusion of the fellow normal eye may reduce its visual acuity and impair binocular vision. Besides recovering visual acuity, some researchers have recommended restoration of stereoacuity and motor fusion and reverse suppression in order to prevent diplopia. Recent studies have documented that the amblyopic visual cortex has a normal complement of cells but reduced spatial resolution and a disordered topographical map. Changes occurring in the late sensitive period selectively impact the parvocellular pathway. Distinct morphophysiologic and psychophysical deficits may demand individualization of therapy, which might provide greater and longer-lasting residual plasticity in some children. |
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Conselho Brasileiro de Oftalmologia |
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2016 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492016000500346 |
| work_keys_str_mv |
AT bretascaiocesarpeixoto amblyopianeuralbasisandtherapeuticapproaches AT sorianorenatonery amblyopianeuralbasisandtherapeuticapproaches |
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