Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks

Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks

ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.

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Main Authors: Yolcu,Umit, Gundogan,Fatih C., Diner,Oktay
Format: Digital revista
Language:English
Published: Conselho Brasileiro de Oftalmologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257
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spelling oai:scielo:S0004-274920150004002572015-09-09Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaksYolcu,UmitGundogan,Fatih C.Diner,Oktay Angioid streaks Antibodies, monoclonal/therapeutic use Antibodies, monoclonal/drug effects Antibodies, monoclonal, humanized/drug effects Choroidal neovascularization/drug therapy Case reports ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.info:eu-repo/semantics/openAccessConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia v.78 n.4 20152015-08-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257en10.5935/0004-2749.20150067
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Yolcu,Umit
Gundogan,Fatih C.
Diner,Oktay
spellingShingle Yolcu,Umit
Gundogan,Fatih C.
Diner,Oktay
Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
author_facet Yolcu,Umit
Gundogan,Fatih C.
Diner,Oktay
author_sort Yolcu,Umit
title Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
title_short Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
title_full Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
title_fullStr Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
title_full_unstemmed Drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
title_sort drastic effect of ranibizumab on choroidal neovascularization in idiopathic angioid streaks
description ABSTRACTA 28-year-old man presented with bilateral vision loss. His best-corrected visual acuity (BCVA) was 0.3 in the right eye (OD) and 0.6 in the left eye (OS). Fundoscopy and fluorescein angiography showed angioid streaks encircling the optic discs of both eyes (OU). Spectral Domain Optical Coherence Tomography (SD-OCT) showed bilateral macular serous detachment. Systemic and ocular screening tests showed no specific cause for the angioid streaks. The patient had previously received pegaptanib sodium injection on three occasions, photodynamic therapy in OS, and no treatment in OD. Upon intravitreal injection of ranibizumab (twice in OU), subretinal fluid was nearly eliminated in OU. BCVA increased to 0.6 in OD and 0.9 in OS, and remained improved until 6 months after treatment.
publisher Conselho Brasileiro de Oftalmologia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000400257
work_keys_str_mv AT yolcuumit drasticeffectofranibizumabonchoroidalneovascularizationinidiopathicangioidstreaks
AT gundoganfatihc drasticeffectofranibizumabonchoroidalneovascularizationinidiopathicangioidstreaks
AT dineroktay drasticeffectofranibizumabonchoroidalneovascularizationinidiopathicangioidstreaks
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