Brown adipose tissue: what have we learned since its recent identification in human adults

Brown adipose tissue: what have we learned since its recent identification in human adults

Brown adipose tissue, an essential organ for thermoregulation in small and hibernating mammals due to its mitochondrial uncoupling capacity, was until recently considered to be present in humans only in newborns. The identification of brown adipose tissue in adult humans since the development and use of positron emission tomography marked with 18-fluorodeoxyglucose (PET-FDG) has raised a series of doubts and questions about its real importance in our metabolism. In this review, we will discuss what we have learnt since its identification in humans as well as both new and old concepts, some of which have been marginalized for decades, such as diet-induced thermogenesis. Arq Bras Endocrinol Metab. 2014;58(9):889-99

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Main Authors: Halpern,Bruno, Mancini,Marcio Correa, Halpern,Alfredo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Endocrinologia e Metabologia 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000900889
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spelling oai:scielo:S0004-273020140009008892015-01-20Brown adipose tissue: what have we learned since its recent identification in human adultsHalpern,BrunoMancini,Marcio CorreaHalpern,Alfredo Brown adipose tissue obesity thermogenesis UCP-1 energy expenditure Brown adipose tissue, an essential organ for thermoregulation in small and hibernating mammals due to its mitochondrial uncoupling capacity, was until recently considered to be present in humans only in newborns. The identification of brown adipose tissue in adult humans since the development and use of positron emission tomography marked with 18-fluorodeoxyglucose (PET-FDG) has raised a series of doubts and questions about its real importance in our metabolism. In this review, we will discuss what we have learnt since its identification in humans as well as both new and old concepts, some of which have been marginalized for decades, such as diet-induced thermogenesis. Arq Bras Endocrinol Metab. 2014;58(9):889-99info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArquivos Brasileiros de Endocrinologia & Metabologia v.58 n.9 20142014-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000900889en10.1590/0004-2730000003492
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Halpern,Bruno
Mancini,Marcio Correa
Halpern,Alfredo
spellingShingle Halpern,Bruno
Mancini,Marcio Correa
Halpern,Alfredo
Brown adipose tissue: what have we learned since its recent identification in human adults
author_facet Halpern,Bruno
Mancini,Marcio Correa
Halpern,Alfredo
author_sort Halpern,Bruno
title Brown adipose tissue: what have we learned since its recent identification in human adults
title_short Brown adipose tissue: what have we learned since its recent identification in human adults
title_full Brown adipose tissue: what have we learned since its recent identification in human adults
title_fullStr Brown adipose tissue: what have we learned since its recent identification in human adults
title_full_unstemmed Brown adipose tissue: what have we learned since its recent identification in human adults
title_sort brown adipose tissue: what have we learned since its recent identification in human adults
description Brown adipose tissue, an essential organ for thermoregulation in small and hibernating mammals due to its mitochondrial uncoupling capacity, was until recently considered to be present in humans only in newborns. The identification of brown adipose tissue in adult humans since the development and use of positron emission tomography marked with 18-fluorodeoxyglucose (PET-FDG) has raised a series of doubts and questions about its real importance in our metabolism. In this review, we will discuss what we have learnt since its identification in humans as well as both new and old concepts, some of which have been marginalized for decades, such as diet-induced thermogenesis. Arq Bras Endocrinol Metab. 2014;58(9):889-99
publisher Sociedade Brasileira de Endocrinologia e Metabologia
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302014000900889
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AT mancinimarciocorrea brownadiposetissuewhathavewelearnedsinceitsrecentidentificationinhumanadults
AT halpernalfredo brownadiposetissuewhathavewelearnedsinceitsrecentidentificationinhumanadults
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