Postprandial glycemia and cardiovascular disease in diabetes mellitus

This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association.

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Main Author: Wajchenberg,Bernardo Léo
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Endocrinologia e Metabologia 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000200010
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spelling oai:scielo:S0004-273020070002000102007-05-02Postprandial glycemia and cardiovascular disease in diabetes mellitusWajchenberg,Bernardo Léo Diabetes mellitus Impaired fasting glucose Glucose intolerance Cardiovascular disease Postprandial glycemia This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association.info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArquivos Brasileiros de Endocrinologia & Metabologia v.51 n.2 20072007-03-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000200010en10.1590/S0004-27302007000200010
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Wajchenberg,Bernardo Léo
spellingShingle Wajchenberg,Bernardo Léo
Postprandial glycemia and cardiovascular disease in diabetes mellitus
author_facet Wajchenberg,Bernardo Léo
author_sort Wajchenberg,Bernardo Léo
title Postprandial glycemia and cardiovascular disease in diabetes mellitus
title_short Postprandial glycemia and cardiovascular disease in diabetes mellitus
title_full Postprandial glycemia and cardiovascular disease in diabetes mellitus
title_fullStr Postprandial glycemia and cardiovascular disease in diabetes mellitus
title_full_unstemmed Postprandial glycemia and cardiovascular disease in diabetes mellitus
title_sort postprandial glycemia and cardiovascular disease in diabetes mellitus
description This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association.
publisher Sociedade Brasileira de Endocrinologia e Metabologia
publishDate 2007
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000200010
work_keys_str_mv AT wajchenbergbernardoleo postprandialglycemiaandcardiovasculardiseaseindiabetesmellitus
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