Postprandial glycemia and cardiovascular disease in diabetes mellitus
This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association.
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Sociedade Brasileira de Endocrinologia e Metabologia
2007
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oai:scielo:S0004-273020070002000102007-05-02Postprandial glycemia and cardiovascular disease in diabetes mellitusWajchenberg,Bernardo Léo Diabetes mellitus Impaired fasting glucose Glucose intolerance Cardiovascular disease Postprandial glycemia This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association.info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArquivos Brasileiros de Endocrinologia & Metabologia v.51 n.2 20072007-03-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000200010en10.1590/S0004-27302007000200010 |
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Wajchenberg,Bernardo Léo |
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Wajchenberg,Bernardo Léo Postprandial glycemia and cardiovascular disease in diabetes mellitus |
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Wajchenberg,Bernardo Léo |
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Wajchenberg,Bernardo Léo |
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Postprandial glycemia and cardiovascular disease in diabetes mellitus |
title_short |
Postprandial glycemia and cardiovascular disease in diabetes mellitus |
title_full |
Postprandial glycemia and cardiovascular disease in diabetes mellitus |
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Postprandial glycemia and cardiovascular disease in diabetes mellitus |
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Postprandial glycemia and cardiovascular disease in diabetes mellitus |
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postprandial glycemia and cardiovascular disease in diabetes mellitus |
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This article reviews the role of fasting and postprandial glycemia to the overall glycemic control of patients with type 2 diabetes and glucose intolerance, as well as their causal relationship upon micro and macrovascular complications. Recent studies have suggested that a third component of the glucose triad, the postprandial glucose excursions, might have a role in the overall glycemic load and might also reflect glycemic control. Epidemiological and intervention studies are presented in the article, supporting the conclusion that postprandial hyperglycemia in impaired glucose tolerance and diabetic subjects is a more powerful marker of cardiovascular disease risk than fasting hyperglycemia, then the treatment directed at specifically lowering postprandial glucose is crucial, as underlined by the American Diabetes Association. |
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Sociedade Brasileira de Endocrinologia e Metabologia |
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2007 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000200010 |
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AT wajchenbergbernardoleo postprandialglycemiaandcardiovasculardiseaseindiabetesmellitus |
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