Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients

AIM: To analyze the relationship between visceral obesity and urinary albumin excretion rate (UAER). METHODS: A cross-sectional study of 73 normoalbuminuric (urinary albumin excretion rate < 20 µg/min) type 2 patients was performed. Patients were divided into two groups according to the median of UAER (7.5 µg/min). Office auscultatory blood pressure was measured in sitting position after a 10-min rest. RESULTS: Waist to hip ratio was higher in the group with UAER > 7.0 µg/min (0.98 ± 0.08), when compared to the other group (0.93 ± 0.08, p= 0.01). Waist to hip ratio significantly correlated with UAER (r= 0.28; p= 0.018). In multiple linear regression analysis, only waist to hip ratio was associated with UAER (r= 0.29; p= 0.04). A1c, DM duration and systolic BP levels were excluded from the model. CONCLUSIONS: Type 2 normoalbuminuric diabetic patients with higher levels of UAER could represent a group with an elevated risk for the development of cardiovascular diseases.

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Main Authors: Pecis,Miriam, Zaslavsky,Lérida M.A., Mallmann,Fabrício B., Pante,Larissa, Krahe,Ana L.D., Stringhari,Fernanda F., Canani,Luis H.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Endocrinologia e Metabologia 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302006000300009
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spelling oai:scielo:S0004-273020060003000092006-08-22Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patientsPecis,MiriamZaslavsky,Lérida M.A.Mallmann,Fabrício B.Pante,LarissaKrahe,Ana L.D.Stringhari,Fernanda F.Canani,Luis H. Diabetes Visceral obesity Albuminuria Waist-hip ratio AIM: To analyze the relationship between visceral obesity and urinary albumin excretion rate (UAER). METHODS: A cross-sectional study of 73 normoalbuminuric (urinary albumin excretion rate < 20 µg/min) type 2 patients was performed. Patients were divided into two groups according to the median of UAER (7.5 µg/min). Office auscultatory blood pressure was measured in sitting position after a 10-min rest. RESULTS: Waist to hip ratio was higher in the group with UAER > 7.0 µg/min (0.98 ± 0.08), when compared to the other group (0.93 ± 0.08, p= 0.01). Waist to hip ratio significantly correlated with UAER (r= 0.28; p= 0.018). In multiple linear regression analysis, only waist to hip ratio was associated with UAER (r= 0.29; p= 0.04). A1c, DM duration and systolic BP levels were excluded from the model. CONCLUSIONS: Type 2 normoalbuminuric diabetic patients with higher levels of UAER could represent a group with an elevated risk for the development of cardiovascular diseases.info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArquivos Brasileiros de Endocrinologia &amp; Metabologia v.50 n.3 20062006-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302006000300009en10.1590/S0004-27302006000300009
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language English
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author Pecis,Miriam
Zaslavsky,Lérida M.A.
Mallmann,Fabrício B.
Pante,Larissa
Krahe,Ana L.D.
Stringhari,Fernanda F.
Canani,Luis H.
spellingShingle Pecis,Miriam
Zaslavsky,Lérida M.A.
Mallmann,Fabrício B.
Pante,Larissa
Krahe,Ana L.D.
Stringhari,Fernanda F.
Canani,Luis H.
Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
author_facet Pecis,Miriam
Zaslavsky,Lérida M.A.
Mallmann,Fabrício B.
Pante,Larissa
Krahe,Ana L.D.
Stringhari,Fernanda F.
Canani,Luis H.
author_sort Pecis,Miriam
title Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
title_short Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
title_full Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
title_fullStr Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
title_full_unstemmed Visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
title_sort visceral obesity is associated with higher urinary albumin excretion levels in normoalbuminuric type 2 diabetic patients
description AIM: To analyze the relationship between visceral obesity and urinary albumin excretion rate (UAER). METHODS: A cross-sectional study of 73 normoalbuminuric (urinary albumin excretion rate < 20 µg/min) type 2 patients was performed. Patients were divided into two groups according to the median of UAER (7.5 µg/min). Office auscultatory blood pressure was measured in sitting position after a 10-min rest. RESULTS: Waist to hip ratio was higher in the group with UAER > 7.0 µg/min (0.98 ± 0.08), when compared to the other group (0.93 ± 0.08, p= 0.01). Waist to hip ratio significantly correlated with UAER (r= 0.28; p= 0.018). In multiple linear regression analysis, only waist to hip ratio was associated with UAER (r= 0.29; p= 0.04). A1c, DM duration and systolic BP levels were excluded from the model. CONCLUSIONS: Type 2 normoalbuminuric diabetic patients with higher levels of UAER could represent a group with an elevated risk for the development of cardiovascular diseases.
publisher Sociedade Brasileira de Endocrinologia e Metabologia
publishDate 2006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302006000300009
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