5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours
OBJECTIVE: To determine the stunning effect of a tracer dose of 5mCi iodine-131. PATIENTS AND METHODS: We retrospectively analyzed 145 patients who received the first ablative treatment at our service. Patients were divided according to disease status determined upon post-treatment scanning (101 patients with thyroid remnants and 44 with pulmonary metastases) and whole-body scanning before ablation (performed on 69 individuals). All patients with thyroid remnants were treated with an ablative dose of 100mCi and those with metastases received 200mCi. RESULTS: In patients with remnants only (n= 41) or metastases (n= 28) submitted to diagnostic scanning, uptake was found to be apparently increased in most patientscases (71 and 73%, respectively) 7 days after therapy, while reduced uptake (visual) was not observed in any patient. The efficacy of ablation was similar in the groups submitted or not to diagnostic scanning: 71 and 80% in patients without metastases (p= 0.28), respectively, and 43 and 50% in those with pulmonary involvement (p= 0.64). CONCLUSION: The present results indicate that diagnostic scanning using a 5mCi iodine-131 dose does not interfere with uptake of the ablative dose or with treatment efficacy when ablation is performed within 72h.
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Sociedade Brasileira de Endocrinologia e Metabologia
2005
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oai:scielo:S0004-273020050003000142005-10-135mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hoursRosário,Pedro Weslley S.Barroso,Álvaro LuísRezende,Leonardo L.Padrão,Eduardo LanzaMaia,Frederico F. RibeiroFagundes,Tales A.Purisch,Saulo Scanning Stunning Thyroid carcinoma OBJECTIVE: To determine the stunning effect of a tracer dose of 5mCi iodine-131. PATIENTS AND METHODS: We retrospectively analyzed 145 patients who received the first ablative treatment at our service. Patients were divided according to disease status determined upon post-treatment scanning (101 patients with thyroid remnants and 44 with pulmonary metastases) and whole-body scanning before ablation (performed on 69 individuals). All patients with thyroid remnants were treated with an ablative dose of 100mCi and those with metastases received 200mCi. RESULTS: In patients with remnants only (n= 41) or metastases (n= 28) submitted to diagnostic scanning, uptake was found to be apparently increased in most patientscases (71 and 73%, respectively) 7 days after therapy, while reduced uptake (visual) was not observed in any patient. The efficacy of ablation was similar in the groups submitted or not to diagnostic scanning: 71 and 80% in patients without metastases (p= 0.28), respectively, and 43 and 50% in those with pulmonary involvement (p= 0.64). CONCLUSION: The present results indicate that diagnostic scanning using a 5mCi iodine-131 dose does not interfere with uptake of the ablative dose or with treatment efficacy when ablation is performed within 72h.info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArquivos Brasileiros de Endocrinologia & Metabologia v.49 n.3 20052005-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302005000300014en10.1590/S0004-27302005000300014 |
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Rosário,Pedro Weslley S. Barroso,Álvaro Luís Rezende,Leonardo L. Padrão,Eduardo Lanza Maia,Frederico F. Ribeiro Fagundes,Tales A. Purisch,Saulo |
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Rosário,Pedro Weslley S. Barroso,Álvaro Luís Rezende,Leonardo L. Padrão,Eduardo Lanza Maia,Frederico F. Ribeiro Fagundes,Tales A. Purisch,Saulo 5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
author_facet |
Rosário,Pedro Weslley S. Barroso,Álvaro Luís Rezende,Leonardo L. Padrão,Eduardo Lanza Maia,Frederico F. Ribeiro Fagundes,Tales A. Purisch,Saulo |
author_sort |
Rosário,Pedro Weslley S. |
title |
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
title_short |
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
title_full |
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
title_fullStr |
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
title_full_unstemmed |
5mCi pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
title_sort |
5mci pretreatment scanning does not cause stunning when the ablative dose is administered within 72 hours |
description |
OBJECTIVE: To determine the stunning effect of a tracer dose of 5mCi iodine-131. PATIENTS AND METHODS: We retrospectively analyzed 145 patients who received the first ablative treatment at our service. Patients were divided according to disease status determined upon post-treatment scanning (101 patients with thyroid remnants and 44 with pulmonary metastases) and whole-body scanning before ablation (performed on 69 individuals). All patients with thyroid remnants were treated with an ablative dose of 100mCi and those with metastases received 200mCi. RESULTS: In patients with remnants only (n= 41) or metastases (n= 28) submitted to diagnostic scanning, uptake was found to be apparently increased in most patientscases (71 and 73%, respectively) 7 days after therapy, while reduced uptake (visual) was not observed in any patient. The efficacy of ablation was similar in the groups submitted or not to diagnostic scanning: 71 and 80% in patients without metastases (p= 0.28), respectively, and 43 and 50% in those with pulmonary involvement (p= 0.64). CONCLUSION: The present results indicate that diagnostic scanning using a 5mCi iodine-131 dose does not interfere with uptake of the ablative dose or with treatment efficacy when ablation is performed within 72h. |
publisher |
Sociedade Brasileira de Endocrinologia e Metabologia |
publishDate |
2005 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302005000300014 |
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