Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study
Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflammatory infiltrate in dermis. They presented greater weight, however, less amount of epididymal fat: the weight was increased while they had fat diminished. A positive correlation was observed between lipid content and bacterial load in mice trained at moderate intensity. Animals that were under high intensity exercises presented superior bacterial load on the lymph nodes, increased neutrophil count and circulating lymphocytes, and had leukocyte recruitment to the dermis augmented, when compared to the ones in moderate exercise. These findings suggest that moderate physical activity modulates the immune response in dermal infection caused by S. aureus in a murine model.
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Academia Brasileira de Ciências
2022
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oai:scielo:S0001-376520220003009042022-06-08Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot studyGALANTINI,MARIA P.L.LEAL,LORENA S.RODRIGUES,KARINE B.RIBEIRO,ISRAEL S.PEREIRA,ITALO S.GONÇALVES,CAROLINE V.CALADO,STÉFANO P.M.SANTOS,DENISAR P. DOSMUNIZ,IGOR P.R.SILVA,ROBSON A.A. DA infection mice physical exercise Staphylococcus aureus Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflammatory infiltrate in dermis. They presented greater weight, however, less amount of epididymal fat: the weight was increased while they had fat diminished. A positive correlation was observed between lipid content and bacterial load in mice trained at moderate intensity. Animals that were under high intensity exercises presented superior bacterial load on the lymph nodes, increased neutrophil count and circulating lymphocytes, and had leukocyte recruitment to the dermis augmented, when compared to the ones in moderate exercise. These findings suggest that moderate physical activity modulates the immune response in dermal infection caused by S. aureus in a murine model.info:eu-repo/semantics/openAccessAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências v.94 n.2 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300904en10.1590/0001-3765202220200561 |
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GALANTINI,MARIA P.L. LEAL,LORENA S. RODRIGUES,KARINE B. RIBEIRO,ISRAEL S. PEREIRA,ITALO S. GONÇALVES,CAROLINE V. CALADO,STÉFANO P.M. SANTOS,DENISAR P. DOS MUNIZ,IGOR P.R. SILVA,ROBSON A.A. DA |
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GALANTINI,MARIA P.L. LEAL,LORENA S. RODRIGUES,KARINE B. RIBEIRO,ISRAEL S. PEREIRA,ITALO S. GONÇALVES,CAROLINE V. CALADO,STÉFANO P.M. SANTOS,DENISAR P. DOS MUNIZ,IGOR P.R. SILVA,ROBSON A.A. DA Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
author_facet |
GALANTINI,MARIA P.L. LEAL,LORENA S. RODRIGUES,KARINE B. RIBEIRO,ISRAEL S. PEREIRA,ITALO S. GONÇALVES,CAROLINE V. CALADO,STÉFANO P.M. SANTOS,DENISAR P. DOS MUNIZ,IGOR P.R. SILVA,ROBSON A.A. DA |
author_sort |
GALANTINI,MARIA P.L. |
title |
Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
title_short |
Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
title_full |
Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
title_fullStr |
Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
title_full_unstemmed |
Physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
title_sort |
physical activity reduces intradermal bacterial load in a murine model submitted to forced swim training – a pilot study |
description |
Abstract Regular exercise is beneficial to health. This study evaluated the effects of moderate and intense physical exercise modalities on intradermal infection by Staphylococcus aureus in a murine model. Mice that practiced moderate exercise had lower bacterial load on lymph nodes and less inflammatory infiltrate in dermis. They presented greater weight, however, less amount of epididymal fat: the weight was increased while they had fat diminished. A positive correlation was observed between lipid content and bacterial load in mice trained at moderate intensity. Animals that were under high intensity exercises presented superior bacterial load on the lymph nodes, increased neutrophil count and circulating lymphocytes, and had leukocyte recruitment to the dermis augmented, when compared to the ones in moderate exercise. These findings suggest that moderate physical activity modulates the immune response in dermal infection caused by S. aureus in a murine model. |
publisher |
Academia Brasileira de Ciências |
publishDate |
2022 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000300904 |
work_keys_str_mv |
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