Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.

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Bibliographic Details
Main Authors: Pinheiro,Eduardo A.A., Carvalho,Josiwander M., Santos,Diellem C.P. dos, Feitosa,André O., Marinho,Patrícia S.B., Guilhon,Giselle Maria S.P., Santos,Lourivaldo S., Souza,Afonso L.D. de, Marinho,Andrey M.R.
Format: Digital revista
Language:English
Published: Academia Brasileira de Ciências 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401247
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