Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.

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Main Authors: Pinheiro,Eduardo A.A., Carvalho,Josiwander M., Santos,Diellem C.P. dos, Feitosa,André O., Marinho,Patrícia S.B., Guilhon,Giselle Maria S.P., Santos,Lourivaldo S., Souza,Afonso L.D. de, Marinho,Andrey M.R.
Format: Digital revista
Language:English
Published: Academia Brasileira de Ciências 2013
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401247
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spelling oai:scielo:S0001-376520130004012472015-11-03Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activityPinheiro,Eduardo A.A.Carvalho,Josiwander M.Santos,Diellem C.P. dosFeitosa,André O.Marinho,Patrícia S.B.Guilhon,Giselle Maria S.P.Santos,Lourivaldo S.Souza,Afonso L.D. deMarinho,Andrey M.R. chemical constituents antimicrobial assay Aspergillus Bauhinia guianensis The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.info:eu-repo/semantics/openAccessAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências v.85 n.4 20132013-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401247en10.1590/0001-3765201395512
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Pinheiro,Eduardo A.A.
Carvalho,Josiwander M.
Santos,Diellem C.P. dos
Feitosa,André O.
Marinho,Patrícia S.B.
Guilhon,Giselle Maria S.P.
Santos,Lourivaldo S.
Souza,Afonso L.D. de
Marinho,Andrey M.R.
spellingShingle Pinheiro,Eduardo A.A.
Carvalho,Josiwander M.
Santos,Diellem C.P. dos
Feitosa,André O.
Marinho,Patrícia S.B.
Guilhon,Giselle Maria S.P.
Santos,Lourivaldo S.
Souza,Afonso L.D. de
Marinho,Andrey M.R.
Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
author_facet Pinheiro,Eduardo A.A.
Carvalho,Josiwander M.
Santos,Diellem C.P. dos
Feitosa,André O.
Marinho,Patrícia S.B.
Guilhon,Giselle Maria S.P.
Santos,Lourivaldo S.
Souza,Afonso L.D. de
Marinho,Andrey M.R.
author_sort Pinheiro,Eduardo A.A.
title Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
title_short Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
title_full Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
title_fullStr Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
title_full_unstemmed Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
title_sort chemical constituents of aspergillus sp ejc08 isolated as endophyte from bauhinia guianensis and their antimicrobial activity
description The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.
publisher Academia Brasileira de Ciências
publishDate 2013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401247
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