Neonatal enteric complex in andean alpacas
Advances in research on the major causative agents of morbidity and mortality in newborn alpacas associated with enteric processes in southern Peru were reviewed. Microbiology and molecular analyses performed on intestinal samples from enterotoxemia fatalities confirmed the predominance of C. perfringens type A carrying only the gene coding for the major α exotoxin and identifiying for the first time the presence of the novel β2 toxin gene. In vitro studies have yielded three profiles for phospholipase activity (high, medium and low) with biological activity when high and medium strains were inoculated intraintestinally in mice and rabbits, but did not induce intestinal pathology in an alpaca cria. A detailed histopathological investigation has reveled that within necrotizing hemorrhagic enteritis Clostridium coexist with massive presence of Eimeria macusaniensis suggesting that primary parasite tissue destruction may well predispose overgrowth of clostridium and toxin production, triggering enteric fatalities. Additionally, studies on diarrheas intestinal swabs and/or intestinal contents identified Escherichia coli pathogenic strains (enteropathogenic and enterohemorrhagic). The immunofluorescent direct test and PCR revealed the presence of Giardia intestinalis coexisting with mostly enteropathogenic and enterohemorrhagic E. coli strains, as well as with a virus similar to bovine coronavirus. These microbes are potentially diarrheagenic pathogens and a possible infection source for Andean people.
Main Authors: | Rosadio A., Raúl, Maturrano H., Lenin, Pérez J., David, Luna E., Luis |
---|---|
Format: | Digital revista |
Language: | spa |
Published: |
Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
2012
|
Online Access: | https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/908 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Molecular genotyping and subtyping of Clostridium perfringens isolated from fatal enterotoxemia in alpacas
by: Pérez, David, et al.
Published: (2012) -
IgG serum concentrations in alpacas neonates killed by enterotoxemia
by: Maximiliano G., Jorge, et al.
Published: (2018) -
Genotypification, in vitro toxigenic evaluation, and antibiotic sensitivity of Escherichia coli strains isolated from diarrheic and fatal cases in neonatal alpacas
by: Luna E., Luis, et al.
Published: (2012) -
ASSOCIATION OF BACTERIAL AND VIRAL AGENTS IN ACUTE PNEUMONIA IN YOUNG ALPACAS
by: Guzmán M., Karol, et al.
Published: (2013) -
Genetic diversity analysis of Pasteurella multocida isolates from alpacas with clinical signs of pneumonia
by: Rímac B., Rocío, et al.
Published: (2017)