GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES

GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES

The aim of this study was to describe gastric, hepatic, and renal lesions inThoroughbred Racing horses associated to the equine gastric ulcer syndrome. Thirtyhorses with a history of gastric ulcer syndrome and recurrent colic during 2006 to 2007 atthe Race Track «La Rinconada», Caracas, Venezuela were evaluated. Horses were euthanized and the necropsy was conducted. Tissue samples were collected from stomach,liver and kidney, and processed by conventional histological methods. In the stomach,the mucosa was intact but areas of hyperaemia and hyperkeratosis were observed in 6cases, multifocal small erosions or ulcers in 6 cases, multifocal large ulcers with areas ofextensive erosion in 12 cases and extensive areas of ulceration with exposure of thesubmucosa in 6 cases. The macroscopic evaluation of the liver showed evidenthepatomegaly in 22 cases and lobular pattern in 18 cases. The kidneys showed severecongestion in all cases, loss of cortico-medullar ratio in 20 cases, cortical necrosis in 18cases, acute tubular necrosis in all cases, papillary necrosis in 6 cases, and adherence ofthe capsule with interstitial fibroplasia in 4 cases. Lesions in the gastric mucosa, liver andkidney were associated with extended treatment with non-steroidal anti-inflammatorydrugs

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Main Authors: Morales B., Abelardo, García G., Francisco, Bermúdez G., Víctor, Sogbe M., Elías, Perdigón M., Miguel
Format: Digital revista
Language:spa
Published: Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria 2011
Online Access:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/283
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spelling oai:ojs.csi.unmsm:article-2832020-03-19T22:20:28Z GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES LESIONES GÁSTRICAS, HEPÁTICAS Y RENALES EN EL SÍNDROME DE ÚLCERAS GÁSTRICAS EN EQUINOS PURA SANGRE DE CARRERA. Morales B., Abelardo García G., Francisco Bermúdez G., Víctor Sogbe M., Elías Perdigón M., Miguel Equinos patología gastritis digestivo hígado renal Síndrome de Úlceras Gástricas equine pathology gastritis digestive liver kidney equine gastric ulcersyndrome The aim of this study was to describe gastric, hepatic, and renal lesions inThoroughbred Racing horses associated to the equine gastric ulcer syndrome. Thirtyhorses with a history of gastric ulcer syndrome and recurrent colic during 2006 to 2007 atthe Race Track «La Rinconada», Caracas, Venezuela were evaluated. Horses were euthanized and the necropsy was conducted. Tissue samples were collected from stomach,liver and kidney, and processed by conventional histological methods. In the stomach,the mucosa was intact but areas of hyperaemia and hyperkeratosis were observed in 6cases, multifocal small erosions or ulcers in 6 cases, multifocal large ulcers with areas ofextensive erosion in 12 cases and extensive areas of ulceration with exposure of thesubmucosa in 6 cases. The macroscopic evaluation of the liver showed evidenthepatomegaly in 22 cases and lobular pattern in 18 cases. The kidneys showed severecongestion in all cases, loss of cortico-medullar ratio in 20 cases, cortical necrosis in 18cases, acute tubular necrosis in all cases, papillary necrosis in 6 cases, and adherence ofthe capsule with interstitial fibroplasia in 4 cases. Lesions in the gastric mucosa, liver andkidney were associated with extended treatment with non-steroidal anti-inflammatorydrugs El objetivo del estudio fue describir lesiones gástricas, hepáticas y renales en caballos Pura Sangre de Carreras enmarcadas en el síndrome ulceroso gástrico equino. Se trabajó con 30 ejemplares Pura Sangre de Carrera con historia de síndrome ulceroso gástrico y cólico recurrentes entre 2006 y 2007, en el Hipódromo «La Rinconada», Caracas, Venezuela. A los animales se les practicó la eutanasia y se colectó nuestras de tejido gástrico, hepático y renal. Las muestras fueron procesadas por los métodos histológicos convencionales. En el estómago se observó mucosa intacta, pero con áreas de hiperemia y/o hiperqueratosis en 6 casos, pequeñas erosiones multifocales o úlceras en 30 casos, úlceras grandes multifocales con regiones extensas de erosión en 12 casos, y úlceras extensivas con áreas de exposición de la submucosa en 6 casos. La evaluación macroscópica del hígado evidenció icteria en 22 casos, así como hepatomegalia y patrón lobulillar en 18 casos. Los riñones mostraron congestión severa en todos los casos, pérdida de la relación córtico medular en 20 casos, necrosis cortical 18 casos, necrosis tubular aguda en todos los casos, necrosis papilar confluente en 6 casos y adherencia de la cápsula con fibroplasia intersticial en 4 casos. Las lesiones observadas en la mucosa gástrica, hígado y riñón estuvieron asociadas con terapéuticas prolongadas con antiinflamatorios no esteroideos. Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria 2011-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article application/pdf https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/283 10.15381/rivep.v22i2.283 Revista de Investigaciones Veterinarias del Perú; Vol. 22 No. 2 (2011); 133-137 Revista de Investigaciones Veterinarias del Perú; Vol. 22 Núm. 2 (2011); 133-137 1682-3419 1609-9117 spa https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/283/261 Derechos de autor 2011 Abelardo Morales B., Francisco García G., Víctor Bermúdez G., Elías Sogbe M., Miguel Perdigón M. https://creativecommons.org/licenses/by-nc-sa/4.0
institution UNMSM
collection OJS
country Perú
countrycode PE
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databasecode rev-rivep
tag revista
region America del Sur
libraryname Biblioteca de la Facultad de Medicina Veterinaria
language spa
format Digital
author Morales B., Abelardo
García G., Francisco
Bermúdez G., Víctor
Sogbe M., Elías
Perdigón M., Miguel
spellingShingle Morales B., Abelardo
García G., Francisco
Bermúdez G., Víctor
Sogbe M., Elías
Perdigón M., Miguel
GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
author_facet Morales B., Abelardo
García G., Francisco
Bermúdez G., Víctor
Sogbe M., Elías
Perdigón M., Miguel
author_sort Morales B., Abelardo
title GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
title_short GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
title_full GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
title_fullStr GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
title_full_unstemmed GASTRIC, LIVERAND RENAL LESIONS ASSOCIATED TO THE SYNDROME OF GASTRIC ULCERS IN THOROUGHBRED HORSES
title_sort gastric, liverand renal lesions associated to the syndrome of gastric ulcers in thoroughbred horses
description The aim of this study was to describe gastric, hepatic, and renal lesions inThoroughbred Racing horses associated to the equine gastric ulcer syndrome. Thirtyhorses with a history of gastric ulcer syndrome and recurrent colic during 2006 to 2007 atthe Race Track «La Rinconada», Caracas, Venezuela were evaluated. Horses were euthanized and the necropsy was conducted. Tissue samples were collected from stomach,liver and kidney, and processed by conventional histological methods. In the stomach,the mucosa was intact but areas of hyperaemia and hyperkeratosis were observed in 6cases, multifocal small erosions or ulcers in 6 cases, multifocal large ulcers with areas ofextensive erosion in 12 cases and extensive areas of ulceration with exposure of thesubmucosa in 6 cases. The macroscopic evaluation of the liver showed evidenthepatomegaly in 22 cases and lobular pattern in 18 cases. The kidneys showed severecongestion in all cases, loss of cortico-medullar ratio in 20 cases, cortical necrosis in 18cases, acute tubular necrosis in all cases, papillary necrosis in 6 cases, and adherence ofthe capsule with interstitial fibroplasia in 4 cases. Lesions in the gastric mucosa, liver andkidney were associated with extended treatment with non-steroidal anti-inflammatorydrugs
publisher Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
publishDate 2011
url https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/283
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