EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS

EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS

The aim of the study was to determine the effect of toltrazuril (2.5%) in a single dose for the treatment of canine sarcocystiosis. Twenty-four crossbred puppies, both sexes, 2.5 months of age, were used. All puppies were dewormed prior to the study and fed throughout the study with a diet free of raw meat. Animals were experimentally infected with nearly 95,000 cysts of S. lamacanis, contained in 100 g of alpaca heart, and distributed in a control (untreated) group of 4 puppies and 4 groups of 5 puppies each which were treated with toltrazuril (2.5%) with a single dose of 10 or 20 mg/kg body weight on day 5 or 7 post-infection. Fecal samples were daily collected during 11 days and starting on day 10 post-infection. Feces was analyzed by the flotation method with the Sheather solution to determine the presence of sporocysts of Sarcocystis sp. and positive samples were analyzed by the modified Stoll method to determine the number of sporocysts per gram of feces. The toltrazuril did not control the infection of S. lamacanis in none of the treated groups.

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Main Authors: Vilca M., Julio, Vilca S, Feliciana, Chávez V., Amanda, Urviola S., Martín, Leyva V., Víctor
Format: Digital revista
Language:spa
Published: Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria 2007
Online Access:https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1278
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spelling oai:ojs.csi.unmsm:article-12782020-03-13T01:02:14Z EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS EFECTO DEL TOLTRAZURIL AL 2.5% DURANTE EL PERIODO PREPATENTE DE LA SARCOCISTIOSIS INTESTINAL CANINA. Vilca M., Julio Vilca S, Feliciana Chávez V., Amanda Urviola S., Martín Leyva V., Víctor Toltrazuril sarcocistiosis control efectividad coccidiosis toltrazuril sarcocystosis control effectiveness coccidiosis The aim of the study was to determine the effect of toltrazuril (2.5%) in a single dose for the treatment of canine sarcocystiosis. Twenty-four crossbred puppies, both sexes, 2.5 months of age, were used. All puppies were dewormed prior to the study and fed throughout the study with a diet free of raw meat. Animals were experimentally infected with nearly 95,000 cysts of S. lamacanis, contained in 100 g of alpaca heart, and distributed in a control (untreated) group of 4 puppies and 4 groups of 5 puppies each which were treated with toltrazuril (2.5%) with a single dose of 10 or 20 mg/kg body weight on day 5 or 7 post-infection. Fecal samples were daily collected during 11 days and starting on day 10 post-infection. Feces was analyzed by the flotation method with the Sheather solution to determine the presence of sporocysts of Sarcocystis sp. and positive samples were analyzed by the modified Stoll method to determine the number of sporocysts per gram of feces. The toltrazuril did not control the infection of S. lamacanis in none of the treated groups. El objetivo del estudio fue determinar el efecto del toltrazuril al 2.5% en dosis única para el tratamiento de la sarcocistiosis intestinal de perros infectados experimentalmente con Sarcocystis lamacanis. Se utilizaron 24 cachorros cruzados de ambos sexos, de 2.5 meses de edad, previamente desparasitados y alimentados con dieta libre de carne cruda. Los perros fueron infectados con cerca de 95,000 quistes de S. lamacanis, presentes en 100 g de músculo cardiaco de alpaca. Se les distribuyó en un grupo control no tratado de cachorros y cuatro grupos de 5 animales c/u tratados con toltrazuril al 2.5% en dosis única de 10 ó 20 mg/kg de peso vivo, administrado oralmente al 5º ó 7º día post-infección. Las muestras fecales fueron recolectadas diariamente, a partir del 10º día post-infección por 11 días. Se analizó las heces por el método de concentración por flotación con solución Sheather para determinar la presencia de esporoquistes, y las muestras positivas se analizaron con el método de Stoll modificado para determinar el número de esporoquistes por gramo de heces. El toltrazuril no logró controlar la infección por S. lamacanis en caninos en ninguno de sus tratamientos. Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria 2007-07-16 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article application/pdf https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1278 10.15381/rivep.v18i1.1278 Revista de Investigaciones Veterinarias del Perú; Vol. 18 No. 1 (2007); 64-68 Revista de Investigaciones Veterinarias del Perú; Vol. 18 Núm. 1 (2007); 64-68 1682-3419 1609-9117 spa https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1278/1076 Derechos de autor 2007 Julio Vilca M., Feliciana Vilca S, Amanda Chávez V., Martín Urviola S., Víctor Leyva V. https://creativecommons.org/licenses/by-nc-sa/4.0
institution UNMSM
collection OJS
country Perú
countrycode PE
component Revista
access En linea
databasecode rev-rivep
tag revista
region America del Sur
libraryname Biblioteca de la Facultad de Medicina Veterinaria
language spa
format Digital
author Vilca M., Julio
Vilca S, Feliciana
Chávez V., Amanda
Urviola S., Martín
Leyva V., Víctor
spellingShingle Vilca M., Julio
Vilca S, Feliciana
Chávez V., Amanda
Urviola S., Martín
Leyva V., Víctor
EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
author_facet Vilca M., Julio
Vilca S, Feliciana
Chávez V., Amanda
Urviola S., Martín
Leyva V., Víctor
author_sort Vilca M., Julio
title EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
title_short EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
title_full EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
title_fullStr EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
title_full_unstemmed EFFECT OF TOLTRAZURIL 2.5% DURING THE PREPATENT PERIOD OF CANINE SARCOCYSTIOSIS
title_sort effect of toltrazuril 2.5% during the prepatent period of canine sarcocystiosis
description The aim of the study was to determine the effect of toltrazuril (2.5%) in a single dose for the treatment of canine sarcocystiosis. Twenty-four crossbred puppies, both sexes, 2.5 months of age, were used. All puppies were dewormed prior to the study and fed throughout the study with a diet free of raw meat. Animals were experimentally infected with nearly 95,000 cysts of S. lamacanis, contained in 100 g of alpaca heart, and distributed in a control (untreated) group of 4 puppies and 4 groups of 5 puppies each which were treated with toltrazuril (2.5%) with a single dose of 10 or 20 mg/kg body weight on day 5 or 7 post-infection. Fecal samples were daily collected during 11 days and starting on day 10 post-infection. Feces was analyzed by the flotation method with the Sheather solution to determine the presence of sporocysts of Sarcocystis sp. and positive samples were analyzed by the modified Stoll method to determine the number of sporocysts per gram of feces. The toltrazuril did not control the infection of S. lamacanis in none of the treated groups.
publisher Universidad Nacional Mayor de San Marcos, Facultad de Medicina Veterinaria
publishDate 2007
url https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/1278
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