Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives
Summary. Samples of cisternal or lumbar cerebrospinal fluid were obtained from 20 young male volunteers born and living at high altitude (3500 to 4800 m). The pH, carbon dioxide and oxygen tensions, and bicarbonate concentration were measured and compared with those in the arterial and jugular venous blood. A consistent difference between the two CSF compartments was noted, particularly a lower pH (0.05), a higher Pco₂, (7 Torr), and lower Po₂ (7 Torr) at the lumbar site. Mean bicarbonate concentration was not significantly different at, the two sites. The main factor is Pco₂ which controls the pH variation. These differences were more marked in high-altitude natives than in man at sea level. The existence of a consistent inhomogeneity of CSF acid-base content emphasizes the inaccuracy of using lumbar CSF pH to estimate the ECF pH as regulator of pulmonary ventilation and determinant of cerebral blood flow.
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| Language: | English |
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Pflügers Arch.
1975
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| Subjects: | EQUILIBRIO ÁCIDO-BASE, PRESIÓN PARCIAL DE OXÍGENO, FLUIDO CEREBROESPINAL, GRAN ALTURA, |
| Online Access: | http://repositorio.umsa.bo/xmlui/handle/123456789/12230 |
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oai:localhost:8080:123456789-122302020-09-04T02:31:29Z Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives Blayo, MC Coudert, J Pocidalo, JJ EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA Summary. Samples of cisternal or lumbar cerebrospinal fluid were obtained from 20 young male volunteers born and living at high altitude (3500 to 4800 m). The pH, carbon dioxide and oxygen tensions, and bicarbonate concentration were measured and compared with those in the arterial and jugular venous blood. A consistent difference between the two CSF compartments was noted, particularly a lower pH (0.05), a higher Pco₂, (7 Torr), and lower Po₂ (7 Torr) at the lumbar site. Mean bicarbonate concentration was not significantly different at, the two sites. The main factor is Pco₂ which controls the pH variation. These differences were more marked in high-altitude natives than in man at sea level. The existence of a consistent inhomogeneity of CSF acid-base content emphasizes the inaccuracy of using lumbar CSF pH to estimate the ECF pH as regulator of pulmonary ventilation and determinant of cerebral blood flow. 2017-08-25T13:57:02Z 2017-08-25T13:57:02Z 1975 Article http://repositorio.umsa.bo/xmlui/handle/123456789/12230 en application/pdf Pflügers Arch. |
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| topic |
EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA |
| spellingShingle |
EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA Blayo, MC Coudert, J Pocidalo, JJ Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| description |
Summary. Samples of cisternal or lumbar cerebrospinal fluid were obtained from 20 young male
volunteers born and living at high altitude (3500 to 4800 m). The pH, carbon dioxide and oxygen tensions, and bicarbonate concentration were measured and compared with those in the arterial and jugular venous blood.
A consistent difference between the two CSF compartments was noted, particularly a lower pH (0.05), a higher Pco₂, (7 Torr), and lower Po₂ (7 Torr) at the lumbar site. Mean bicarbonate concentration was not significantly different at, the two sites. The main factor is Pco₂ which controls the pH variation.
These differences were more marked in high-altitude natives than in man at sea level.
The existence of a consistent inhomogeneity of CSF acid-base content emphasizes the inaccuracy of using lumbar CSF pH to estimate the ECF pH as regulator of pulmonary ventilation and determinant of cerebral blood flow. |
| format |
Article |
| topic_facet |
EQUILIBRIO ÁCIDO-BASE PRESIÓN PARCIAL DE OXÍGENO FLUIDO CEREBROESPINAL GRAN ALTURA |
| author |
Blayo, MC Coudert, J Pocidalo, JJ |
| author_facet |
Blayo, MC Coudert, J Pocidalo, JJ |
| author_sort |
Blayo, MC |
| title |
Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| title_short |
Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| title_full |
Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| title_fullStr |
Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| title_full_unstemmed |
Comparison of cisternal and lumbar cerebrospinal fluid pH in high altitude natives |
| title_sort |
comparison of cisternal and lumbar cerebrospinal fluid ph in high altitude natives |
| publisher |
Pflügers Arch. |
| publishDate |
1975 |
| url |
http://repositorio.umsa.bo/xmlui/handle/123456789/12230 |
| work_keys_str_mv |
AT blayomc comparisonofcisternalandlumbarcerebrospinalfluidphinhighaltitudenatives AT coudertj comparisonofcisternalandlumbarcerebrospinalfluidphinhighaltitudenatives AT pocidalojj comparisonofcisternalandlumbarcerebrospinalfluidphinhighaltitudenatives |
| _version_ |
1766395060878835712 |