Furfural analysis of aqueous and oily foodstuffs using a single modified paper for combined headspace extraction, derivatization and paper spray mass spectrometry
Furfurals, including 2-furaldehyde, 5-methylfurfural and 5-hydroxymethylfurfural, widely exist in carbohydrate-rich daily foods, and may have toxic effects on humans. Here, a new headspace extraction-paper spray mass spectrometry (HSPS-MS/MS) method was established for furfural detection, in which the extraction and derivatization of volatiles with pre-loaded derivatization agent on paper tips is combined with paper spray mass spectrometry for detection. By this simple and cheap approach, interference of non-volatile matrix compounds is prevented, and the derivatization agent improves electrospray-type ionization efficiency, thus increasing selectivity and sensitivity. The approach was optimized, by investigating positioning during extraction, extraction duration, derivatization agent, addition of internal standard for quantification and finally validated. For this, the developed method was benchmarked against HPLC-UV and could obtain detections limits of 0.32–0.40 μg mL−1 for 2-furaldehyde, 5-methylfurfural and 5-hydroxymethylfurfural in olive oil. Moreover, fast screening of free furfurals in soy sauce, coffees and teas was demonstrated with the HSPS-MS/MS method.
Main Authors: | Luo, Wei, Qin, Yu, van Beek, Teris A., Chen, Bo, Zuilhof, Han, Salentijn, Gert |
---|---|
Format: | Article/Letter to editor biblioteca |
Language: | English |
Subjects: | Food quality control, Furfurals analysis, Paper modification, Paper spray mass spectrometry, Selective derivatization and enrichment, |
Online Access: | https://research.wur.nl/en/publications/furfural-analysis-of-aqueous-and-oily-foodstuffs-using-a-single-m |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Bifunctional Ti4+-modified paper for selective extraction or removal of phospholipids and paper spray mass spectrometry for bioanalysis in urine and plasma
by: Luo, Wei, et al. -
Novel Selectivity-Based Forensic Toxicological Validation of a Paper Spray Mass Spectrometry Method for the Quantitative Determination of Eight Amphetamines in Whole Blood
by: Teunissen, Sebastiaan F., et al. -
Ionization of glycans from alkali metal salt-impregnated paper
by: Guo, Ping, et al. -
Rapid multiresidue determination of bisphenol analogues in soil with on-line derivatization
by: Pérez Martín, Rosa Ana, et al.
Published: (2017) -
Rapid Determination of Clonidine in Pharmaceutical Preparations by Paper Spray Tandem Mass Spectrometry (PS-MS/MS)
by: Luo, Wei, et al.