Immune signaling: receptor-like proteins make the difference
To resist biotic attacks, plants have evolved a sophisticated, receptor-based immune system. Cell-surface immune receptors, which are either receptor-like kinases (RLKs) or receptor-like proteins (RLPs), form the front line of the plant defense machinery. RLPs lack a cytoplasmic kinase domain for downstream immune signaling, and leucine-rich repeat (LRR)-containing RLPs constitutively associate with the RLK SOBIR1. The RLP/SOBIR1 complex was proposed to be the bimolecular equivalent of genuine RLKs. However, it appears that the molecular mechanisms by which RLP/SOBIR1 complexes and RLKs mount immunity show some striking differences. Here, we summarize the differences between RLP/SOBIR1 and RLK signaling, focusing on the way these receptors recruit the BAK1 co-receptor and elaborating on the negative crosstalk taking place between the two signaling networks.
Main Authors: | , |
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Format: | Article/Letter to editor biblioteca |
Language: | English |
Subjects: | SOBIR1, cell-surface immune receptors, crosstalk, immune signaling, leucine-rich repeat receptor-like kinases (RLKs), leucine-rich repeat receptor-like proteins (RLPs), |
Online Access: | https://research.wur.nl/en/publications/immune-signaling-receptor-like-proteins-make-the-difference |
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