Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)

Growth and nutrition during early life have been strongly linked to future health and metabolic risks. The Cambridge Baby Growth Study (CBGS), a longitudinal birth cohort of 2229 mother– infant pairs, was set up in 2001 to investigate early life determinant factors of infant growth and body composition in the UK setting. To carry out extensive profiling of breastmilk intakes and composition in relation to infancy growth, the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF) was established upon the original CBGS. The strict inclusion criteria were applied, focusing on a normal birth weight vaginally delivered infant cohort born of healthy and non-obese mothers. Crucially, only infants who were exclusively breastfed for the first 6 weeks of life were retained in the analysed study sample. At each visit from birth, 2 weeks, 6 weeks, and then at 3, 6, 12, 24, and 36 months, longitudinal anthropometric measurements and blood spot collections were conducted. Infant body composition was assessed using air displacement plethysmography (ADP) at 6 weeks and 3 months of age. Breast milk was collected for macronutrients and human milk oligosaccharides (HMO) measurements. Breast milk intake volume was also estimated, as well as sterile breastmilk and infant stool collection for microbiome study.

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Main Authors: Olga, Laurentya, Petry, Clive J., van Diepen, Janna A., Prentice, Philippa M., Hughes, Ieuan A., Vervoort, Jacques, Boekhorst, Jos, Chichlowski, Maciej, Gross, Gabriele, Dunger, David B., Ong, Ken K.
Format: Article/Letter to editor biblioteca
Language:English
Subjects:Breast milk, Breast milk nutrients, Breastfeeding, Childhood obesity, Cohort profile, Early life, Human milk oligosaccharides, Infant growth, Infant nutrition, Prevention,
Online Access:https://research.wur.nl/en/publications/extensive-study-of-breast-milk-and-infant-growth-protocol-of-the-
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spelling dig-wur-nl-wurpubs-5866772024-10-02 Olga, Laurentya Petry, Clive J. van Diepen, Janna A. Prentice, Philippa M. Hughes, Ieuan A. Vervoort, Jacques Boekhorst, Jos Chichlowski, Maciej Gross, Gabriele Dunger, David B. Ong, Ken K. Article/Letter to editor Nutrients 13 (2021) 8 ISSN: 2072-6643 Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF) 2021 Growth and nutrition during early life have been strongly linked to future health and metabolic risks. The Cambridge Baby Growth Study (CBGS), a longitudinal birth cohort of 2229 mother– infant pairs, was set up in 2001 to investigate early life determinant factors of infant growth and body composition in the UK setting. To carry out extensive profiling of breastmilk intakes and composition in relation to infancy growth, the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF) was established upon the original CBGS. The strict inclusion criteria were applied, focusing on a normal birth weight vaginally delivered infant cohort born of healthy and non-obese mothers. Crucially, only infants who were exclusively breastfed for the first 6 weeks of life were retained in the analysed study sample. At each visit from birth, 2 weeks, 6 weeks, and then at 3, 6, 12, 24, and 36 months, longitudinal anthropometric measurements and blood spot collections were conducted. Infant body composition was assessed using air displacement plethysmography (ADP) at 6 weeks and 3 months of age. Breast milk was collected for macronutrients and human milk oligosaccharides (HMO) measurements. Breast milk intake volume was also estimated, as well as sterile breastmilk and infant stool collection for microbiome study. en application/pdf https://research.wur.nl/en/publications/extensive-study-of-breast-milk-and-infant-growth-protocol-of-the- 10.3390/nu13082879 https://edepot.wur.nl/553411 Breast milk Breast milk nutrients Breastfeeding Childhood obesity Cohort profile Early life Human milk oligosaccharides Infant growth Infant nutrition Prevention https://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/ Wageningen University & Research
institution WUR NL
collection DSpace
country Países bajos
countrycode NL
component Bibliográfico
access En linea
databasecode dig-wur-nl
tag biblioteca
region Europa del Oeste
libraryname WUR Library Netherlands
language English
topic Breast milk
Breast milk nutrients
Breastfeeding
Childhood obesity
Cohort profile
Early life
Human milk oligosaccharides
Infant growth
Infant nutrition
Prevention
Breast milk
Breast milk nutrients
Breastfeeding
Childhood obesity
Cohort profile
Early life
Human milk oligosaccharides
Infant growth
Infant nutrition
Prevention
spellingShingle Breast milk
Breast milk nutrients
Breastfeeding
Childhood obesity
Cohort profile
Early life
Human milk oligosaccharides
Infant growth
Infant nutrition
Prevention
Breast milk
Breast milk nutrients
Breastfeeding
Childhood obesity
Cohort profile
Early life
Human milk oligosaccharides
Infant growth
Infant nutrition
Prevention
Olga, Laurentya
Petry, Clive J.
van Diepen, Janna A.
Prentice, Philippa M.
Hughes, Ieuan A.
Vervoort, Jacques
Boekhorst, Jos
Chichlowski, Maciej
Gross, Gabriele
Dunger, David B.
Ong, Ken K.
Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
description Growth and nutrition during early life have been strongly linked to future health and metabolic risks. The Cambridge Baby Growth Study (CBGS), a longitudinal birth cohort of 2229 mother– infant pairs, was set up in 2001 to investigate early life determinant factors of infant growth and body composition in the UK setting. To carry out extensive profiling of breastmilk intakes and composition in relation to infancy growth, the Cambridge Baby Growth and Breastfeeding Study (CBGS-BF) was established upon the original CBGS. The strict inclusion criteria were applied, focusing on a normal birth weight vaginally delivered infant cohort born of healthy and non-obese mothers. Crucially, only infants who were exclusively breastfed for the first 6 weeks of life were retained in the analysed study sample. At each visit from birth, 2 weeks, 6 weeks, and then at 3, 6, 12, 24, and 36 months, longitudinal anthropometric measurements and blood spot collections were conducted. Infant body composition was assessed using air displacement plethysmography (ADP) at 6 weeks and 3 months of age. Breast milk was collected for macronutrients and human milk oligosaccharides (HMO) measurements. Breast milk intake volume was also estimated, as well as sterile breastmilk and infant stool collection for microbiome study.
format Article/Letter to editor
topic_facet Breast milk
Breast milk nutrients
Breastfeeding
Childhood obesity
Cohort profile
Early life
Human milk oligosaccharides
Infant growth
Infant nutrition
Prevention
author Olga, Laurentya
Petry, Clive J.
van Diepen, Janna A.
Prentice, Philippa M.
Hughes, Ieuan A.
Vervoort, Jacques
Boekhorst, Jos
Chichlowski, Maciej
Gross, Gabriele
Dunger, David B.
Ong, Ken K.
author_facet Olga, Laurentya
Petry, Clive J.
van Diepen, Janna A.
Prentice, Philippa M.
Hughes, Ieuan A.
Vervoort, Jacques
Boekhorst, Jos
Chichlowski, Maciej
Gross, Gabriele
Dunger, David B.
Ong, Ken K.
author_sort Olga, Laurentya
title Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
title_short Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
title_full Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
title_fullStr Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
title_full_unstemmed Extensive study of breast milk and infant growth : Protocol of the Cambridge baby growth and breastfeeding study (CBGS-BF)
title_sort extensive study of breast milk and infant growth : protocol of the cambridge baby growth and breastfeeding study (cbgs-bf)
url https://research.wur.nl/en/publications/extensive-study-of-breast-milk-and-infant-growth-protocol-of-the-
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