Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly
Aging is accompanied with increased frailty and comorbidities, which is potentially associated with microbiome perturbations. Dietary fibers could contribute to healthy aging by beneficially impacting gut microbiota and metabolite profiles. We aimed to compare young adults with elderly and investigate the effect of pectin supplementation on fecal microbiota composition, short chain fatty acids (SCFAs), and exhaled volatile organic compounds (VOCs) while using a randomized, double-blind, placebo-controlled parallel design. Fifty-two young adults and 48 elderly consumed 15 g/day sugar beet pectin or maltodextrin for four weeks. Fecal and exhaled breath samples were collected before and after the intervention period. Fecal samples were used for microbiota profiling by 16S rRNA gene amplicon sequencing, and for analysis of SCFAs by gas chromatography (GC). Breath was used for VOC analysis by GC-tof-MS. Young adults and elderly showed similar fecal SCFA and exhaled VOC profiles. Additionally, fecal microbiota profiles were similar, with five genera significantly different in relative abundance. Pectin supplementation did not significantly alter fecal microbiota, SCFA or exhaled VOC profiles in elderly or young adults. In conclusion, aside from some minor differences in microbial composition, healthy elderly and young adults showed comparable fecal microbiota composition and activity, which were not altered by pectin supplementation.
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article/Letter to editor biblioteca |
| Language: | English |
| Subjects: | ERP114374, PRJEB31775, aging, dietary fiber, elderly, exhaled air, microbiota, pectin, young adults, |
| Online Access: | https://research.wur.nl/en/publications/sugar-beet-pectin-supplementation-did-not-alter-profiles-of-fecal |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-wur-nl-wurpubs-554549 |
|---|---|
| record_format |
koha |
| spelling |
dig-wur-nl-wurpubs-5545492024-10-30 An, Ran Wilms, Ellen Smolinska, Agnieszka Hermes, Gerben D.A. Masclee, Ad A.M. de Vos, Paul Schols, Henk A. van Schooten, Frederik J. Smidt, Hauke Jonkers, Daisy M.A.E. Zoetendal, Erwin G. Troost, Freddy J. Article/Letter to editor Nutrients 11 (2019) 9 ISSN: 2072-6643 Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly 2019 Aging is accompanied with increased frailty and comorbidities, which is potentially associated with microbiome perturbations. Dietary fibers could contribute to healthy aging by beneficially impacting gut microbiota and metabolite profiles. We aimed to compare young adults with elderly and investigate the effect of pectin supplementation on fecal microbiota composition, short chain fatty acids (SCFAs), and exhaled volatile organic compounds (VOCs) while using a randomized, double-blind, placebo-controlled parallel design. Fifty-two young adults and 48 elderly consumed 15 g/day sugar beet pectin or maltodextrin for four weeks. Fecal and exhaled breath samples were collected before and after the intervention period. Fecal samples were used for microbiota profiling by 16S rRNA gene amplicon sequencing, and for analysis of SCFAs by gas chromatography (GC). Breath was used for VOC analysis by GC-tof-MS. Young adults and elderly showed similar fecal SCFA and exhaled VOC profiles. Additionally, fecal microbiota profiles were similar, with five genera significantly different in relative abundance. Pectin supplementation did not significantly alter fecal microbiota, SCFA or exhaled VOC profiles in elderly or young adults. In conclusion, aside from some minor differences in microbial composition, healthy elderly and young adults showed comparable fecal microbiota composition and activity, which were not altered by pectin supplementation. en application/pdf https://research.wur.nl/en/publications/sugar-beet-pectin-supplementation-did-not-alter-profiles-of-fecal 10.3390/nu11092193 https://edepot.wur.nl/502425 ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults https://creativecommons.org/licenses/by/4.0/ Wageningen University & Research |
| institution |
WUR NL |
| collection |
DSpace |
| country |
Países bajos |
| countrycode |
NL |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-wur-nl |
| tag |
biblioteca |
| region |
Europa del Oeste |
| libraryname |
WUR Library Netherlands |
| language |
English |
| topic |
ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults |
| spellingShingle |
ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults An, Ran Wilms, Ellen Smolinska, Agnieszka Hermes, Gerben D.A. Masclee, Ad A.M. de Vos, Paul Schols, Henk A. van Schooten, Frederik J. Smidt, Hauke Jonkers, Daisy M.A.E. Zoetendal, Erwin G. Troost, Freddy J. Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| description |
Aging is accompanied with increased frailty and comorbidities, which is potentially associated with microbiome perturbations. Dietary fibers could contribute to healthy aging by beneficially impacting gut microbiota and metabolite profiles. We aimed to compare young adults with elderly and investigate the effect of pectin supplementation on fecal microbiota composition, short chain fatty acids (SCFAs), and exhaled volatile organic compounds (VOCs) while using a randomized, double-blind, placebo-controlled parallel design. Fifty-two young adults and 48 elderly consumed 15 g/day sugar beet pectin or maltodextrin for four weeks. Fecal and exhaled breath samples were collected before and after the intervention period. Fecal samples were used for microbiota profiling by 16S rRNA gene amplicon sequencing, and for analysis of SCFAs by gas chromatography (GC). Breath was used for VOC analysis by GC-tof-MS. Young adults and elderly showed similar fecal SCFA and exhaled VOC profiles. Additionally, fecal microbiota profiles were similar, with five genera significantly different in relative abundance. Pectin supplementation did not significantly alter fecal microbiota, SCFA or exhaled VOC profiles in elderly or young adults. In conclusion, aside from some minor differences in microbial composition, healthy elderly and young adults showed comparable fecal microbiota composition and activity, which were not altered by pectin supplementation. |
| format |
Article/Letter to editor |
| topic_facet |
ERP114374 PRJEB31775 aging dietary fiber elderly exhaled air microbiota pectin young adults |
| author |
An, Ran Wilms, Ellen Smolinska, Agnieszka Hermes, Gerben D.A. Masclee, Ad A.M. de Vos, Paul Schols, Henk A. van Schooten, Frederik J. Smidt, Hauke Jonkers, Daisy M.A.E. Zoetendal, Erwin G. Troost, Freddy J. |
| author_facet |
An, Ran Wilms, Ellen Smolinska, Agnieszka Hermes, Gerben D.A. Masclee, Ad A.M. de Vos, Paul Schols, Henk A. van Schooten, Frederik J. Smidt, Hauke Jonkers, Daisy M.A.E. Zoetendal, Erwin G. Troost, Freddy J. |
| author_sort |
An, Ran |
| title |
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| title_short |
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| title_full |
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| title_fullStr |
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| title_full_unstemmed |
Sugar Beet Pectin Supplementation Did Not Alter Profiles of Fecal Microbiota and Exhaled Breath in Healthy Young Adults and Healthy Elderly |
| title_sort |
sugar beet pectin supplementation did not alter profiles of fecal microbiota and exhaled breath in healthy young adults and healthy elderly |
| url |
https://research.wur.nl/en/publications/sugar-beet-pectin-supplementation-did-not-alter-profiles-of-fecal |
| work_keys_str_mv |
AT anran sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT wilmsellen sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT smolinskaagnieszka sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT hermesgerbenda sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT mascleeadam sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT devospaul sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT scholshenka sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT vanschootenfrederikj sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT smidthauke sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT jonkersdaisymae sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT zoetendalerwing sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly AT troostfreddyj sugarbeetpectinsupplementationdidnotalterprofilesoffecalmicrobiotaandexhaledbreathinhealthyyoungadultsandhealthyelderly |
| _version_ |
1816156490415734784 |