Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.
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dig-wur-nl-wurpubs-5521892024-12-04 Bouhid de Aguiar, Izabella Meireles, Martine Bouchoux, Antoine Schroën, Karin Article/Letter to editor Scientific Reports 9 (2019) ISSN: 2045-2322 Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions 2019 Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle. en application/pdf https://research.wur.nl/en/publications/conformational-changes-influence-clogging-behavior-of-micrometer- 10.1038/s41598-019-45791-y https://edepot.wur.nl/496113 Life Science https://creativecommons.org/licenses/by/4.0/ Wageningen University & Research |
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Life Science Life Science Bouhid de Aguiar, Izabella Meireles, Martine Bouchoux, Antoine Schroën, Karin Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
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Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle. |
format |
Article/Letter to editor |
topic_facet |
Life Science |
author |
Bouhid de Aguiar, Izabella Meireles, Martine Bouchoux, Antoine Schroën, Karin |
author_facet |
Bouhid de Aguiar, Izabella Meireles, Martine Bouchoux, Antoine Schroën, Karin |
author_sort |
Bouhid de Aguiar, Izabella |
title |
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
title_short |
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
title_full |
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
title_fullStr |
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
title_full_unstemmed |
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
title_sort |
conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions |
url |
https://research.wur.nl/en/publications/conformational-changes-influence-clogging-behavior-of-micrometer- |
work_keys_str_mv |
AT bouhiddeaguiarizabella conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions AT meirelesmartine conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions AT bouchouxantoine conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions AT schroenkarin conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions |
_version_ |
1819145597964255232 |