Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions

Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.

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Main Authors: Bouhid de Aguiar, Izabella, Meireles, Martine, Bouchoux, Antoine, Schroën, Karin
Format: Article/Letter to editor biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/conformational-changes-influence-clogging-behavior-of-micrometer-
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spelling dig-wur-nl-wurpubs-5521892024-12-04 Bouhid de Aguiar, Izabella Meireles, Martine Bouchoux, Antoine Schroën, Karin Article/Letter to editor Scientific Reports 9 (2019) ISSN: 2045-2322 Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions 2019 Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle. en application/pdf https://research.wur.nl/en/publications/conformational-changes-influence-clogging-behavior-of-micrometer- 10.1038/s41598-019-45791-y https://edepot.wur.nl/496113 Life Science https://creativecommons.org/licenses/by/4.0/ Wageningen University & Research
institution WUR NL
collection DSpace
country Países bajos
countrycode NL
component Bibliográfico
access En linea
databasecode dig-wur-nl
tag biblioteca
region Europa del Oeste
libraryname WUR Library Netherlands
language English
topic Life Science
Life Science
spellingShingle Life Science
Life Science
Bouhid de Aguiar, Izabella
Meireles, Martine
Bouchoux, Antoine
Schroën, Karin
Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
description Clogging of porous media by soft particles has become a subject of extensive research in the last years and the understanding of the clogging mechanisms is of great importance for process optimization. The rise in the utilization of microfluidic devices brought the possibility to simulate membrane filtration and perform in situ observations of the pore clogging mechanisms with the aid of high speed cameras. In this work, we use microfluidic devices composed by an array of parallel channels to observe the clogging behavior of micrometer sized microgels. It is important to note that the microgels are larger than the pores/constrictions. We quantify the clog propensity in relation to the clogging position and particle size and find that the majority of the microgels clog at the first constriction independently of particle size and constriction entrance angle. We also quantify the variations in shape and volume (2D projection) of the microgels in relation to particle size and constriction entrance angle. We find that the degree of deformation increases with particle size and is dependent of constriction entrance angle, whereas, changes in volume do not depend on entrance angle.
format Article/Letter to editor
topic_facet Life Science
author Bouhid de Aguiar, Izabella
Meireles, Martine
Bouchoux, Antoine
Schroën, Karin
author_facet Bouhid de Aguiar, Izabella
Meireles, Martine
Bouchoux, Antoine
Schroën, Karin
author_sort Bouhid de Aguiar, Izabella
title Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
title_short Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
title_full Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
title_fullStr Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
title_full_unstemmed Conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
title_sort conformational changes influence clogging behavior of micrometer-sized microgels in idealized multiple constrictions
url https://research.wur.nl/en/publications/conformational-changes-influence-clogging-behavior-of-micrometer-
work_keys_str_mv AT bouhiddeaguiarizabella conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions
AT meirelesmartine conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions
AT bouchouxantoine conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions
AT schroenkarin conformationalchangesinfluencecloggingbehaviorofmicrometersizedmicrogelsinidealizedmultipleconstrictions
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