Vaccines for diseases caused by viruses of the family of Reoviridae

The invention relates to methods for producing a propagation- competent strain of a mutant Reoviridae virus, and to a propagation- competent strain of a mutant Reoviridae virus that is obtainable by a method of the invention. The invention further relates to a propagation-competent strain of a mutant Reoviridae virus, comprising a deletion of a genetic region that is relevant for propagation of the virus, and to a vaccine, comprising a propagation-competent strain of a mutant Reoviridae virus.

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Bibliographic Details
Main Authors: van Rijn, P.A., van Gennip, H.G.P., van de Water, S.G.P., Feenstra, F.
Format: Patent biblioteca
Language:English
Subjects:Life Science,
Online Access:https://research.wur.nl/en/publications/vaccines-for-diseases-caused-by-viruses-of-the-family-of-reovirid
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Description
Summary:The invention relates to methods for producing a propagation- competent strain of a mutant Reoviridae virus, and to a propagation- competent strain of a mutant Reoviridae virus that is obtainable by a method of the invention. The invention further relates to a propagation-competent strain of a mutant Reoviridae virus, comprising a deletion of a genetic region that is relevant for propagation of the virus, and to a vaccine, comprising a propagation-competent strain of a mutant Reoviridae virus.