Loss of susceptibility as a novel breeding strategy for durable and broad-spectrum resistance

Recent studies on plant immunity have suggested that a pathogen should suppress induced plant defense in order to infect a plant species, which otherwise would have been a nonhost to the pathogen. For this purpose, pathogens exploit effector molecules to interfere with different layers of plant defense responses. In this review, we summarize the latest findings on plant factors that are activated by pathogen effectors to suppress plant immunity. By looking from a different point of view into host and nonhost resistance, we propose a novel breeding strategy: disabling plant disease susceptibility genes (S-genes) to achieve durable and broad-spectrum resistance

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Bibliographic Details
Main Authors: Pavan, S.N.C., Jacobsen, E., Visser, R.G.F., Bai, Y.
Format: Article/Letter to editor biblioteca
Language:English
Subjects:arabidopsis mutant cev1, barley mlo-gene, gated ion-channel, initiation-factor eif4e, lettuce-mosaic-virus, nonhost resistance, oryzae pv. oryzae, powdery mildew resistance, systemic acquired-resistance, yellow-mottle-virus,
Online Access:https://research.wur.nl/en/publications/loss-of-susceptibility-as-a-novel-breeding-strategy-for-durable-a
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Summary:Recent studies on plant immunity have suggested that a pathogen should suppress induced plant defense in order to infect a plant species, which otherwise would have been a nonhost to the pathogen. For this purpose, pathogens exploit effector molecules to interfere with different layers of plant defense responses. In this review, we summarize the latest findings on plant factors that are activated by pathogen effectors to suppress plant immunity. By looking from a different point of view into host and nonhost resistance, we propose a novel breeding strategy: disabling plant disease susceptibility genes (S-genes) to achieve durable and broad-spectrum resistance