A study of the microbiological reduction of a,B-unsaturated carbonyl ent-kaurenes by Gibberella fujikuroi
The incubation of 18-hydroxy-15-oxo-ent-kaur-16-ene with the fungus Gibberella fujikuroi gave 16a,17-dihydro-15-oxo derivatives, whilst the feeding of 3-oxo-15a,16a-epoxy-ent-kaur-1-ene afforded a series of products, which conserve the 1,2-double bond. These results indicated that the hydrogenation, of a,B-unsaturated carbonyl compunds with an ent-kaurene skeleton by this fungus is a stereospecific and regiospecific reduction, that does not depend on the biosynthetic route of gibberellins and kaurenolides.
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Elsevier
1996
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| Online Access: | http://hdl.handle.net/10261/22151 http://dx.doi.org/10.13039/501100008737 |
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| Summary: | The incubation of 18-hydroxy-15-oxo-ent-kaur-16-ene with the fungus Gibberella fujikuroi gave 16a,17-dihydro-15-oxo derivatives, whilst the feeding of 3-oxo-15a,16a-epoxy-ent-kaur-1-ene afforded a series of products, which conserve the 1,2-double bond. These results indicated that the hydrogenation, of a,B-unsaturated carbonyl compunds with an ent-kaurene skeleton by this fungus is a stereospecific and regiospecific reduction, that does not depend on the biosynthetic route of gibberellins and kaurenolides. |
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