Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates
Adriatoxin-B (ATX-B) is the first C13 terminal truncated YTX analogous metabolite that was isolated from large-scale cultures of the dinoflagellate Protoceratium reticulatum. The structure and conformational behavior of ATX-B was elucidated by a combination of NMR spectroscopy experiments and a conformational analysis. The isolation of this metabolite, which possesses a clear structural relationship with adriatoxin, supports the idea that the real source of these cut down substances is in the microalgae and not in the mollusks, via metabolic degradation like it has been assumed until now.
Main Authors: | , , , , |
---|---|
Other Authors: | |
Format: | artículo biblioteca |
Language: | English |
Published: |
Elsevier
2010-07-06
|
Subjects: | Adriatoxin, Yessotoxin, Marine toxins, DSP syndrome, Marine polyethers, |
Online Access: | http://hdl.handle.net/10261/213301 http://dx.doi.org/10.13039/501100011034 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
dig-ipna-es-10261-213301 |
---|---|
record_format |
koha |
spelling |
dig-ipna-es-10261-2133012020-06-05T01:10:57Z Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates Domínguez, Humberto J. Souto, María L. Norte, Manuel Hernández Daranas, Antonio Fernández, José J. Ministerio de Educación y Cultura (España) CSIC - Instituto Español de Oceanografía (IEO) Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers Adriatoxin-B (ATX-B) is the first C13 terminal truncated YTX analogous metabolite that was isolated from large-scale cultures of the dinoflagellate Protoceratium reticulatum. The structure and conformational behavior of ATX-B was elucidated by a combination of NMR spectroscopy experiments and a conformational analysis. The isolation of this metabolite, which possesses a clear structural relationship with adriatoxin, supports the idea that the real source of these cut down substances is in the microalgae and not in the mollusks, via metabolic degradation like it has been assumed until now. Peer reviewed 2020-06-04T07:56:22Z 2020-06-04T07:56:22Z 2010-07-06 artículo http://purl.org/coar/resource_type/c_6501 Toxicon 55(8): 1484-1490 (2010) 0041-0101 10.1016/j.toxicon.2010.02.029 http://hdl.handle.net/10261/213301 1879-3150 http://dx.doi.org/10.13039/501100011034 en Postprint https://doi.org/10.1016/j.toxicon.2010.02.029 No none Elsevier |
institution |
IPNA ES |
collection |
DSpace |
country |
España |
countrycode |
ES |
component |
Bibliográfico |
access |
En linea |
databasecode |
dig-ipna-es |
tag |
biblioteca |
region |
Europa del Sur |
libraryname |
Biblioteca del IPNA España |
language |
English |
topic |
Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers |
spellingShingle |
Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers Domínguez, Humberto J. Souto, María L. Norte, Manuel Hernández Daranas, Antonio Fernández, José J. Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
description |
Adriatoxin-B (ATX-B) is the first C13 terminal truncated YTX analogous metabolite that was isolated from large-scale cultures of the dinoflagellate Protoceratium reticulatum. The structure and conformational behavior of ATX-B was elucidated by a combination of NMR spectroscopy experiments and a conformational analysis. The isolation of this metabolite, which possesses a clear structural relationship with adriatoxin, supports the idea that the real source of these cut down substances is in the microalgae and not in the mollusks, via metabolic degradation like it has been assumed until now. |
author2 |
Ministerio de Educación y Cultura (España) |
author_facet |
Ministerio de Educación y Cultura (España) Domínguez, Humberto J. Souto, María L. Norte, Manuel Hernández Daranas, Antonio Fernández, José J. |
format |
artículo |
topic_facet |
Adriatoxin Yessotoxin Marine toxins DSP syndrome Marine polyethers |
author |
Domínguez, Humberto J. Souto, María L. Norte, Manuel Hernández Daranas, Antonio Fernández, José J. |
author_sort |
Domínguez, Humberto J. |
title |
Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
title_short |
Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
title_full |
Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
title_fullStr |
Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
title_full_unstemmed |
Adriatoxin-B, the first C13 terminal truncated YTX analogue obtained from dinoflagellates |
title_sort |
adriatoxin-b, the first c13 terminal truncated ytx analogue obtained from dinoflagellates |
publisher |
Elsevier |
publishDate |
2010-07-06 |
url |
http://hdl.handle.net/10261/213301 http://dx.doi.org/10.13039/501100011034 |
work_keys_str_mv |
AT dominguezhumbertoj adriatoxinbthefirstc13terminaltruncatedytxanalogueobtainedfromdinoflagellates AT soutomarial adriatoxinbthefirstc13terminaltruncatedytxanalogueobtainedfromdinoflagellates AT nortemanuel adriatoxinbthefirstc13terminaltruncatedytxanalogueobtainedfromdinoflagellates AT hernandezdaranasantonio adriatoxinbthefirstc13terminaltruncatedytxanalogueobtainedfromdinoflagellates AT fernandezjosej adriatoxinbthefirstc13terminaltruncatedytxanalogueobtainedfromdinoflagellates |
_version_ |
1777669858803056640 |