Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities
Tanzawaic acids M (1), N (2), O (3) and P (4) and the known tanzawaic acids B (5) and E (6), have been isolated from an extract of a cultured marine-derived fungus (strain CF07370) identified as a member of the genus Penicillium. The structures of 1–4 were determined based on spectroscopic evidence. The antimicrobial and cytotoxic activities of compounds 1–6 were evaluated.
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Royal Society of Chemistry (UK)
2015
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| Online Access: | http://hdl.handle.net/10261/181188 http://dx.doi.org/10.13039/501100003725 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100011017 |
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dig-ipna-es-10261-1811882019-05-16T13:26:10Z Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities Cardoso-Martínez, F. Rosa, José M. de la Díaz-Marrero, Ana R. Darias, José Cerella, Claudia Diederich, Marc Cueto, Mercedes Ministerio de Ciencia e Innovación (España) Consejo Superior de Investigaciones Científicas (España) Recherches Scientifiques Luxembourg National Research Foundation of Korea Tanzawaic acids M (1), N (2), O (3) and P (4) and the known tanzawaic acids B (5) and E (6), have been isolated from an extract of a cultured marine-derived fungus (strain CF07370) identified as a member of the genus Penicillium. The structures of 1–4 were determined based on spectroscopic evidence. The antimicrobial and cytotoxic activities of compounds 1–6 were evaluated. This work was supported by the Ministerio de Ciencia e Innovación SAF2009–0839. F. C. acknowledges financial support from Programa JAE-Pre (CSIC). ARDM acknowledges funding from the IMBRAIN project (FP7-REGPOT-2012-CT2012–31637-IMBRAIN). CC is supported by a “Waxweiler grant for cancer prevention research” from the Action Lions “Vaincre le Cancer”, Luxembourg. This work was supported by Télévie Luxembourg, the “Recherche Cancer et Sang” foundation and “Recherches Scientifiques Luxembourg” association. The authors thank the “Een Häerz fir Kriibskrank Kanner” association and the Action Lions “Vaincre le Cancer” for generous support. MD is supported by the National Research Foundation (NRF) by the MEST of Korea for Tumor Microenvironment Global Core Research Center (GCRC) grant, [grant number 2012–0001184]. Peer Reviewed 2019-05-10T07:48:10Z 2019-05-10T07:48:10Z 2015 2019-05-10T07:48:10Z artículo http://purl.org/coar/resource_type/c_6501 Organic and Biomolecular Chemistry 13(26): 7248-7256 (2015) 1477-0520 http://hdl.handle.net/10261/181188 10.1039/c5ob00773a 1477-0539 http://dx.doi.org/10.13039/501100003725 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100011017 #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/EC/FP7/316137 https://doi.org/10.1039/C5OB00773A Sí none Royal Society of Chemistry (UK) |
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Tanzawaic acids M (1), N (2), O (3) and P (4) and the known tanzawaic acids B (5) and E (6), have been isolated from an extract of a cultured marine-derived fungus (strain CF07370) identified as a member of the genus Penicillium. The structures of 1–4 were determined based on spectroscopic evidence. The antimicrobial and cytotoxic activities of compounds 1–6 were evaluated. |
| author2 |
Ministerio de Ciencia e Innovación (España) |
| author_facet |
Ministerio de Ciencia e Innovación (España) Cardoso-Martínez, F. Rosa, José M. de la Díaz-Marrero, Ana R. Darias, José Cerella, Claudia Diederich, Marc Cueto, Mercedes |
| format |
artículo |
| author |
Cardoso-Martínez, F. Rosa, José M. de la Díaz-Marrero, Ana R. Darias, José Cerella, Claudia Diederich, Marc Cueto, Mercedes |
| spellingShingle |
Cardoso-Martínez, F. Rosa, José M. de la Díaz-Marrero, Ana R. Darias, José Cerella, Claudia Diederich, Marc Cueto, Mercedes Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| author_sort |
Cardoso-Martínez, F. |
| title |
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| title_short |
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| title_full |
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| title_fullStr |
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| title_full_unstemmed |
Tanzawaic acids isolated from a marine-derived fungus of the genus Penicillium with cytotoxic activities |
| title_sort |
tanzawaic acids isolated from a marine-derived fungus of the genus penicillium with cytotoxic activities |
| publisher |
Royal Society of Chemistry (UK) |
| publishDate |
2015 |
| url |
http://hdl.handle.net/10261/181188 http://dx.doi.org/10.13039/501100003725 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100011017 |
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