Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio

Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.

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Main Authors: Ruiz-Vasquez, Liliana, Ruiz-Mesía, Lastenia, Reina, Matías, López-Rodríguez, Matías, González-Platas, Javier, Giménez, Cristina, Cabrera, Raimundo, González-Coloma, Azucena
Other Authors: Ministerio de Economía, Industria y Competitividad (España)
Format: artículo biblioteca
Published: Elsevier 2018-12
Subjects:Senecio, Benzofurans, Benzoic acid derivatives, Diterpenes, Pyrrolizidine alkaloids, Asteraceae,
Online Access:http://hdl.handle.net/10261/179474
http://dx.doi.org/10.13039/501100010198
http://dx.doi.org/10.13039/501100003339
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spelling dig-ipna-es-10261-1794742020-12-13T09:10:06Z Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio Ruiz-Vasquez, Liliana Ruiz-Mesía, Lastenia Reina, Matías López-Rodríguez, Matías González-Platas, Javier Giménez, Cristina Cabrera, Raimundo González-Coloma, Azucena Ministerio de Economía, Industria y Competitividad (España) Consejo Superior de Investigaciones Científicas (España) Senecio Benzofurans Benzoic acid derivatives Diterpenes Pyrrolizidine alkaloids Asteraceae Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested. This work has been supported by Grant (CTQ2015-64049-C3-1-R) (MINECO/FEDER) Spain. LRV thanks JAEPRE-DOC-CSIC for predoctoral fellowship. Peer Reviewed 2019-04-05T16:05:01Z 2019-04-05T16:05:01Z 2018-12 2019-04-05T16:05:01Z artículo http://purl.org/coar/resource_type/c_6501 doi: 10.1016/j.phytol.2018.07.002 e-issn: 1876-7486 issn: 1874-3900 Phytochemistry Letters 28: 47-54 (2018) http://hdl.handle.net/10261/179474 10.1016/j.phytol.2018.07.002 http://dx.doi.org/10.13039/501100010198 http://dx.doi.org/10.13039/501100003339 #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2015-64049-C3-1-R Postprint https://doi.org/10.1016/j.phytol.2018.07.002 Sí none Elsevier
institution IPNA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-ipna-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IPNA España
topic Senecio
Benzofurans
Benzoic acid derivatives
Diterpenes
Pyrrolizidine alkaloids
Asteraceae
Senecio
Benzofurans
Benzoic acid derivatives
Diterpenes
Pyrrolizidine alkaloids
Asteraceae
spellingShingle Senecio
Benzofurans
Benzoic acid derivatives
Diterpenes
Pyrrolizidine alkaloids
Asteraceae
Senecio
Benzofurans
Benzoic acid derivatives
Diterpenes
Pyrrolizidine alkaloids
Asteraceae
Ruiz-Vasquez, Liliana
Ruiz-Mesía, Lastenia
Reina, Matías
López-Rodríguez, Matías
González-Platas, Javier
Giménez, Cristina
Cabrera, Raimundo
González-Coloma, Azucena
Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
description Sixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.
author2 Ministerio de Economía, Industria y Competitividad (España)
author_facet Ministerio de Economía, Industria y Competitividad (España)
Ruiz-Vasquez, Liliana
Ruiz-Mesía, Lastenia
Reina, Matías
López-Rodríguez, Matías
González-Platas, Javier
Giménez, Cristina
Cabrera, Raimundo
González-Coloma, Azucena
format artículo
topic_facet Senecio
Benzofurans
Benzoic acid derivatives
Diterpenes
Pyrrolizidine alkaloids
Asteraceae
author Ruiz-Vasquez, Liliana
Ruiz-Mesía, Lastenia
Reina, Matías
López-Rodríguez, Matías
González-Platas, Javier
Giménez, Cristina
Cabrera, Raimundo
González-Coloma, Azucena
author_sort Ruiz-Vasquez, Liliana
title Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
title_short Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
title_full Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
title_fullStr Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
title_full_unstemmed Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
title_sort benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from peruvian senecio
publisher Elsevier
publishDate 2018-12
url http://hdl.handle.net/10261/179474
http://dx.doi.org/10.13039/501100010198
http://dx.doi.org/10.13039/501100003339
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