Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus
5 pages, 2 figures, 1 table.-- Printed version published Jun 23, 2003.
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Format: | artículo biblioteca |
Language: | English |
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Elsevier
2003-06-04
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Subjects: | Labdane diterpenes, Pulmonate, Carcinoma, |
Online Access: | http://hdl.handle.net/10261/13271 http://dx.doi.org/10.13039/501100006280 http://dx.doi.org/10.13039/501100005853 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100002848 |
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dig-ipna-es-10261-132712019-11-13T12:56:32Z Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus Díaz-Marrero, Ana R. Dorta, Enrique Cueto, Mercedes Rovirosa, Juana San Martín, Aurelio Loyola, Luis Alberto Darias, José Gobierno de Canarias Ministerio de Ciencia y Tecnología (España) Universidad de Chile Consejo Superior de Investigaciones Científicas (España) Comisión Nacional de Investigación Científica y Tecnológica (Chile) Universidad de Antofagasta Labdane diterpenes Pulmonate Carcinoma 5 pages, 2 figures, 1 table.-- Printed version published Jun 23, 2003. Four new labdane diterpenes, 1-4, with an unusual oxidation pattern have been isolated from the marine pulmonate Trimusculus peruvianus. The structure and stereochemistry of these compounds were determined by spectroscopic data and chemical transformations. The absolute stereochemistry of 4 was assigned by application of the modified Mosher method. These compounds exhibit in vitro moderate cytotoxic activity against human colon carcinoma cell lines. This work was supported by the Ministerio de Ciencia y Tecnología (MCYT), project ref: PPQ2002-02494, DGUI of the Canary Islands Government PI2002/044, DID project CSMAR 02/6-2 of the Universidad de Chile, Cooperation Programme between CSIC (Spain)–CONICYT (Chile), and DI of the Universidad de Antofagasta. We are grateful to BIOMAR, S.A. for performing the bioassays. A. R. D.-M. acknowledges an I3P grant from the CSIC and E. D. an FPI grant from the MCYT. 2009-05-28T07:15:36Z 2009-05-28T07:15:36Z 2003-06-04 artículo http://purl.org/coar/resource_type/c_6501 Tetrahedron 59(26): 4805-4809 (2003) 0040-4020 http://hdl.handle.net/10261/13271 10.1016/S0040-4020(03)00731-2 http://dx.doi.org/10.13039/501100006280 http://dx.doi.org/10.13039/501100005853 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100002848 en http://dx.doi.org/10.1016/S0040-4020(03)00731-2 none 2373 bytes 129166 bytes text/plain application/pdf Elsevier |
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Labdane diterpenes Pulmonate Carcinoma Labdane diterpenes Pulmonate Carcinoma |
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Labdane diterpenes Pulmonate Carcinoma Labdane diterpenes Pulmonate Carcinoma Díaz-Marrero, Ana R. Dorta, Enrique Cueto, Mercedes Rovirosa, Juana San Martín, Aurelio Loyola, Luis Alberto Darias, José Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
description |
5 pages, 2 figures, 1 table.-- Printed version published Jun 23, 2003. |
author2 |
Gobierno de Canarias |
author_facet |
Gobierno de Canarias Díaz-Marrero, Ana R. Dorta, Enrique Cueto, Mercedes Rovirosa, Juana San Martín, Aurelio Loyola, Luis Alberto Darias, José |
format |
artículo |
topic_facet |
Labdane diterpenes Pulmonate Carcinoma |
author |
Díaz-Marrero, Ana R. Dorta, Enrique Cueto, Mercedes Rovirosa, Juana San Martín, Aurelio Loyola, Luis Alberto Darias, José |
author_sort |
Díaz-Marrero, Ana R. |
title |
Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
title_short |
Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
title_full |
Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
title_fullStr |
Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
title_full_unstemmed |
Labdane diterpenes with a new oxidation pattern from the marine pulmonate Trimusculus peruvianus |
title_sort |
labdane diterpenes with a new oxidation pattern from the marine pulmonate trimusculus peruvianus |
publisher |
Elsevier |
publishDate |
2003-06-04 |
url |
http://hdl.handle.net/10261/13271 http://dx.doi.org/10.13039/501100006280 http://dx.doi.org/10.13039/501100005853 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100002848 |
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