Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects

14 pages, 2 figures, 5 tables.-- Available online Oct 25, 2007.

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Main Authors: Domínguez-Díaz, Dulce, Reina, Matías, Santos-Guerra, Arnoldo, Santana, Omar, Agulló-Ortuño, María Teresa, López-Balboa, Carmen, González-Coloma, Azucena
Other Authors: European Commission
Format: artículo biblioteca
Language:English
Published: Elsevier 2008-03
Subjects:Canarian endemism, Asteraceae, Boraginaceae, Pyrrolizidine alkaloid, Antifeedants, Cytotoxic, Phytotoxic,
Online Access:http://hdl.handle.net/10261/12607
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003339
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spelling dig-ipna-es-10261-126072020-09-16T12:27:44Z Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects Domínguez-Díaz, Dulce Reina, Matías Santos-Guerra, Arnoldo Santana, Omar Agulló-Ortuño, María Teresa López-Balboa, Carmen González-Coloma, Azucena European Commission Consejo Superior de Investigaciones Científicas (España) Canarian endemism Asteraceae Boraginaceae Pyrrolizidine alkaloid Antifeedants Cytotoxic Phytotoxic 14 pages, 2 figures, 5 tables.-- Available online Oct 25, 2007. Pyrrolizidine alkaloid (PA) producing plants belonging to the Boraginaceae (Echium wildpretti) and Asteraceae (Canariothamnus palmensis, Kleinia neriifolia, Pericallis appendiculata, Pericallis echinata, Pericallis hansenii, Pericallis multiflora, Pericallis steetzii and Senecio bollei) were selected to study their alkaloidal composition and the defensive properties (antifeedant and phytotoxic effects) of their ethanolic and alkaloidal extracts plus their isolated PAs against insects (Spodoptera littoralis, Leptinotarsa decemlineata, the aphids Myzus persicae and Rhopalosiphum padi) and Lactuca sativa seeds. We also tested the selective cytotoxic effects of these PAs on insect-derived Sf9 and mammalian CHO cells. Most of the insect antifeedant effects were found in the ethanolic extracts. The isolated PAs had species- and structure-dependent antifeedant effects and all of them decreased L. sativa radicle growth, suggesting a specific mode of action against insects and a generalized one against plants. Given the relatively low alkaloid content of these species, we assume that their herbivore defenses are not only alkaloid-based. This work was supported by grants CTQ2006-15597-C02-01/PPQ and an I3P-CSIC fellowship to D.M. Domínguez. Plant collection was possible thanks to the "Cabildos" of Tenerife, Gomera and Lanzarote. 2009-04-28T07:13:58Z 2009-04-28T07:13:58Z 2008-03 artículo http://purl.org/coar/resource_type/c_6501 Biochemical Systematics and Ecology 36(3): 153-166 (2008) 0305-1978 http://hdl.handle.net/10261/12607 10.1016/j.bse.2007.08.015 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100003339 en http://dx.doi.org/10.1016/j.bse.2007.08.015 none 2373 bytes 407083 bytes text/plain application/pdf Elsevier
institution IPNA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-ipna-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IPNA España
language English
topic Canarian endemism
Asteraceae
Boraginaceae
Pyrrolizidine alkaloid
Antifeedants
Cytotoxic
Phytotoxic
Canarian endemism
Asteraceae
Boraginaceae
Pyrrolizidine alkaloid
Antifeedants
Cytotoxic
Phytotoxic
spellingShingle Canarian endemism
Asteraceae
Boraginaceae
Pyrrolizidine alkaloid
Antifeedants
Cytotoxic
Phytotoxic
Canarian endemism
Asteraceae
Boraginaceae
Pyrrolizidine alkaloid
Antifeedants
Cytotoxic
Phytotoxic
Domínguez-Díaz, Dulce
Reina, Matías
Santos-Guerra, Arnoldo
Santana, Omar
Agulló-Ortuño, María Teresa
López-Balboa, Carmen
González-Coloma, Azucena
Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
description 14 pages, 2 figures, 5 tables.-- Available online Oct 25, 2007.
author2 European Commission
author_facet European Commission
Domínguez-Díaz, Dulce
Reina, Matías
Santos-Guerra, Arnoldo
Santana, Omar
Agulló-Ortuño, María Teresa
López-Balboa, Carmen
González-Coloma, Azucena
format artículo
topic_facet Canarian endemism
Asteraceae
Boraginaceae
Pyrrolizidine alkaloid
Antifeedants
Cytotoxic
Phytotoxic
author Domínguez-Díaz, Dulce
Reina, Matías
Santos-Guerra, Arnoldo
Santana, Omar
Agulló-Ortuño, María Teresa
López-Balboa, Carmen
González-Coloma, Azucena
author_sort Domínguez-Díaz, Dulce
title Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
title_short Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
title_full Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
title_fullStr Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
title_full_unstemmed Pyrrolizidine alkaloids from Canarian endemic plants and their biological effects
title_sort pyrrolizidine alkaloids from canarian endemic plants and their biological effects
publisher Elsevier
publishDate 2008-03
url http://hdl.handle.net/10261/12607
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003339
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