Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems

The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including attenuated virus and DNA and RNA viral vectors. Besides their usefulness in vaccinology, these ADSs constitute invaluable tools to researchers for understanding the nature of protective responses in different species, opening the possibility of modulating or potentiating relevant immune mechanisms involved in protection. © 2008 Elsevier Ltd. All rights reserved.

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Main Authors: Brun, A., Albina, E., Barret, T., Chapman, D. A. G., Czub, M., Dixon, L. K., Keil, G. M., Klonjkowski, B., Le Potier, M. F., Libeau, G., Ortego, J., Richardson, J., Takamatsu, H. H.
Format: review biblioteca
Language:eng
Published: 2008
Online Access:http://hdl.handle.net/20.500.12792/4618
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spelling dig-inia-es-20.500.12792-46182020-12-15T09:54:27Z Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems Brun, A. Albina, E. Barret, T. Chapman, D. A. G. Czub, M. Dixon, L. K. Keil, G. M. Klonjkowski, B. Le Potier, M. F. Libeau, G. Ortego, J. Richardson, J. Takamatsu, H. H. The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including attenuated virus and DNA and RNA viral vectors. Besides their usefulness in vaccinology, these ADSs constitute invaluable tools to researchers for understanding the nature of protective responses in different species, opening the possibility of modulating or potentiating relevant immune mechanisms involved in protection. © 2008 Elsevier Ltd. All rights reserved. 2020-10-22T17:35:22Z 2020-10-22T17:35:22Z 2008 review http://hdl.handle.net/20.500.12792/4618 10.1016/j.vaccine.2008.09.044 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ open access
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country España
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language eng
description The recent advances in molecular genetics, pathogenesis and immunology have provided an optimal framework for developing novel approaches in the rational design of vaccines effective against viral epizootic diseases. This paper reviews most of the viral-vector based antigen delivery systems (ADSs) recently developed for vaccine testing in veterinary species, including attenuated virus and DNA and RNA viral vectors. Besides their usefulness in vaccinology, these ADSs constitute invaluable tools to researchers for understanding the nature of protective responses in different species, opening the possibility of modulating or potentiating relevant immune mechanisms involved in protection. © 2008 Elsevier Ltd. All rights reserved.
format review
author Brun, A.
Albina, E.
Barret, T.
Chapman, D. A. G.
Czub, M.
Dixon, L. K.
Keil, G. M.
Klonjkowski, B.
Le Potier, M. F.
Libeau, G.
Ortego, J.
Richardson, J.
Takamatsu, H. H.
spellingShingle Brun, A.
Albina, E.
Barret, T.
Chapman, D. A. G.
Czub, M.
Dixon, L. K.
Keil, G. M.
Klonjkowski, B.
Le Potier, M. F.
Libeau, G.
Ortego, J.
Richardson, J.
Takamatsu, H. H.
Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
author_facet Brun, A.
Albina, E.
Barret, T.
Chapman, D. A. G.
Czub, M.
Dixon, L. K.
Keil, G. M.
Klonjkowski, B.
Le Potier, M. F.
Libeau, G.
Ortego, J.
Richardson, J.
Takamatsu, H. H.
author_sort Brun, A.
title Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
title_short Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
title_full Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
title_fullStr Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
title_full_unstemmed Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems
title_sort antigen delivery systems for veterinary vaccine development. viral-vector based delivery systems
publishDate 2008
url http://hdl.handle.net/20.500.12792/4618
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