Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size
Here, the effects of incubation temperature and particle size on the dissolution and aggregation behavior of copper nanoparticles (CuNPs) in culture media were investigated over 96 h, equivalent to the time period for acute cell toxicity tests. Three CuNPs with the nominal sizes of 25, 50, and 100 nm and one type of micro-sized particles (MPs, ~500 nm) were examined in culture media used for human and fish hepatoma cell lines acute tests. A large decrease in sizes of CuNPs in the culture media was observed in the first 24 h incubation, and subsequently the sizes of CuNPs changed slightly over the following 72 h. Moreover, the decreasing rate in size was significantly dependent on the incubation temperature; the higher the incubation temperature, the larger the decreasing rate in size. In addition to that, we also found that the release of copper ions depended on the incubation temperature. Moreover, the dissolution rate of Cu particles increased very fast in the first 24 h, with a slight increase over the following 72 h. © 2015, Springer Science+Business Media Dordrecht.
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dig-inia-es-20.500.12792-23892020-12-15T09:48:03Z Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size Li, L. Fernández-Cruz, M. L. Connolly, M. Schuster, M. Navas, J. M. Here, the effects of incubation temperature and particle size on the dissolution and aggregation behavior of copper nanoparticles (CuNPs) in culture media were investigated over 96 h, equivalent to the time period for acute cell toxicity tests. Three CuNPs with the nominal sizes of 25, 50, and 100 nm and one type of micro-sized particles (MPs, ~500 nm) were examined in culture media used for human and fish hepatoma cell lines acute tests. A large decrease in sizes of CuNPs in the culture media was observed in the first 24 h incubation, and subsequently the sizes of CuNPs changed slightly over the following 72 h. Moreover, the decreasing rate in size was significantly dependent on the incubation temperature; the higher the incubation temperature, the larger the decreasing rate in size. In addition to that, we also found that the release of copper ions depended on the incubation temperature. Moreover, the dissolution rate of Cu particles increased very fast in the first 24 h, with a slight increase over the following 72 h. © 2015, Springer Science+Business Media Dordrecht. 2020-10-22T12:54:48Z 2020-10-22T12:54:48Z 2015 journal article http://hdl.handle.net/20.500.12792/2389 10.1007/s11051-015-2865-0 eng Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ open access |
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Here, the effects of incubation temperature and particle size on the dissolution and aggregation behavior of copper nanoparticles (CuNPs) in culture media were investigated over 96 h, equivalent to the time period for acute cell toxicity tests. Three CuNPs with the nominal sizes of 25, 50, and 100 nm and one type of micro-sized particles (MPs, ~500 nm) were examined in culture media used for human and fish hepatoma cell lines acute tests. A large decrease in sizes of CuNPs in the culture media was observed in the first 24 h incubation, and subsequently the sizes of CuNPs changed slightly over the following 72 h. Moreover, the decreasing rate in size was significantly dependent on the incubation temperature; the higher the incubation temperature, the larger the decreasing rate in size. In addition to that, we also found that the release of copper ions depended on the incubation temperature. Moreover, the dissolution rate of Cu particles increased very fast in the first 24 h, with a slight increase over the following 72 h. © 2015, Springer Science+Business Media Dordrecht. |
format |
journal article |
author |
Li, L. Fernández-Cruz, M. L. Connolly, M. Schuster, M. Navas, J. M. |
spellingShingle |
Li, L. Fernández-Cruz, M. L. Connolly, M. Schuster, M. Navas, J. M. Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
author_facet |
Li, L. Fernández-Cruz, M. L. Connolly, M. Schuster, M. Navas, J. M. |
author_sort |
Li, L. |
title |
Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
title_short |
Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
title_full |
Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
title_fullStr |
Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
title_full_unstemmed |
Dissolution and aggregation of Cu nanoparticles in culture media effects of incubation temperature and particles size |
title_sort |
dissolution and aggregation of cu nanoparticles in culture media effects of incubation temperature and particles size |
publishDate |
2015 |
url |
http://hdl.handle.net/20.500.12792/2389 |
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