Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep

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Main Authors: Santos-Jimenez, Zurisaday, Guillen-Gargallo, Sara, Encinas, Teresa, Berlinguer, Fiammetta, Veliz-Deras, F. G., Martinez-Ros, P., González De Bulnes, Antonio
Other Authors: Santos-Jimenez, Zurisaday [0000-0003-3589-1870]
Format: artículo biblioteca
Language:English
Published: Multidisciplinary Digital Publishing Institute 2020-05-21
Subjects:GnRH, eCG, Estrus synchronization, Propylene-glycol, Sheep,
Online Access:http://hdl.handle.net/10261/340890
https://api.elsevier.com/content/abstract/scopus_id/85085175129
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spelling dig-inia-es-10261-3408902024-05-14T20:41:03Z Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep Santos-Jimenez, Zurisaday Guillen-Gargallo, Sara Encinas, Teresa Berlinguer, Fiammetta Veliz-Deras, F. G. Martinez-Ros, P. González De Bulnes, Antonio Santos-Jimenez, Zurisaday [0000-0003-3589-1870] Encinas, Teresa [0000-0002-2985-7257] Berlinguer, Fiammetta [0000-0002-2500-8063] Veliz-Deras, F. G. [0000-0002-5105-1508] Martinez-Ros, P. [0000-0001-7303-0073] González De Bulnes, Antonio [0000-0002-0917-4475] GnRH eCG Estrus synchronization Propylene-glycol Sheep 12 Pág. The foreseen shortage of eCG for estrus synchronization in sheep makes necessary the development of alternative protocols. The aim of the present work was to evaluate the reproductive response of sheep in breeding season to the administration of GnRH using propylene-glycol as a cosolvent and the subcutaneous route for slowing and extending the release of GnRH, as well as the most adequate timing for such administration. In the present study, protocols based on a short-term CIDR treatment and a single subcutaneous dose of GnRH in propylene-glycol at 36 h after CIDR removal induced a similar ovarian response to protocols based on administration of eCG at CIDR removal or intramuscular GnRH in distilled water at 56 h after. In such protocol, 80% of the animals developed estrus in a narrow timing (75% between 36 and 48 h after CIDR removal), and all of them also ovulated in a narrow window (87.5% between 72 and 76 h after CIDR removal, with 62.5% between 72 and 76 h) and showed a similar ovulation rate and plasma progesterone concentrations at the induced estrous cycle. Hence, administration of GnRH in propylene-glycol may constitute an alternative to traditional protocols based on the administration of eCG. This research received no external funding. Peer reviewed 2023-12-19T07:04:04Z 2023-12-19T07:04:04Z 2020-05-21 artículo http://purl.org/coar/resource_type/c_6501 Animals 10(5): e897 (2020) http://hdl.handle.net/10261/340890 10.3390/ani10050897 2076-2615 32455785 2-s2.0-85085175129 https://api.elsevier.com/content/abstract/scopus_id/85085175129 en Departamento de Reproducción Animal​  Publisher's version https://doi.org/10.3390/ani10050897 Sí open application/pdf Multidisciplinary Digital Publishing Institute
institution INIA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-inia-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del INIA España
language English
topic GnRH
eCG
Estrus synchronization
Propylene-glycol
Sheep
GnRH
eCG
Estrus synchronization
Propylene-glycol
Sheep
spellingShingle GnRH
eCG
Estrus synchronization
Propylene-glycol
Sheep
GnRH
eCG
Estrus synchronization
Propylene-glycol
Sheep
Santos-Jimenez, Zurisaday
Guillen-Gargallo, Sara
Encinas, Teresa
Berlinguer, Fiammetta
Veliz-Deras, F. G.
Martinez-Ros, P.
González De Bulnes, Antonio
Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
description 12 Pág.
author2 Santos-Jimenez, Zurisaday [0000-0003-3589-1870]
author_facet Santos-Jimenez, Zurisaday [0000-0003-3589-1870]
Santos-Jimenez, Zurisaday
Guillen-Gargallo, Sara
Encinas, Teresa
Berlinguer, Fiammetta
Veliz-Deras, F. G.
Martinez-Ros, P.
González De Bulnes, Antonio
format artículo
topic_facet GnRH
eCG
Estrus synchronization
Propylene-glycol
Sheep
author Santos-Jimenez, Zurisaday
Guillen-Gargallo, Sara
Encinas, Teresa
Berlinguer, Fiammetta
Veliz-Deras, F. G.
Martinez-Ros, P.
González De Bulnes, Antonio
author_sort Santos-Jimenez, Zurisaday
title Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
title_short Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
title_full Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
title_fullStr Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
title_full_unstemmed Use of Propylene-Glycol as a Cosolvent for GnRH in Synchronization of Estrus and Ovulation in Sheep
title_sort use of propylene-glycol as a cosolvent for gnrh in synchronization of estrus and ovulation in sheep
publisher Multidisciplinary Digital Publishing Institute
publishDate 2020-05-21
url http://hdl.handle.net/10261/340890
https://api.elsevier.com/content/abstract/scopus_id/85085175129
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