Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets
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BioMed Central
2020-11-30
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Subjects: | Ancient DNA, Competitive mapping, DNA contamination removal, Palaeogenomics, |
Online Access: | http://hdl.handle.net/10261/337042 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100009244 https://api.elsevier.com/content/abstract/scopus_id/85096938959 |
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dig-inia-es-10261-3370422024-05-15T20:39:36Z Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets Feuerborn, Tatiana R. Palkopoulou, Eleftheria van der Valk, Tom von Seth, Johanna Munters, Arielle R. Pečnerová, Patrícia Dehasque, Marianne Ureña, Irene Ersmark, Erik Lagerholm, Vendela Kempe Krzewińska, Maja Rodríguez-Varela, Ricardo Götherström, Anders Dalén, Love Díez-Del-Molino, David Swedish Research Council European Commission Stockholm University Feuerborn, Tatiana R. [0000-0003-1610-3402] Palkopoulou, Eleftheria [0000-0001-7382-7509] van der Valk, Tom [0000-0001-6582-3452] von Seth, Johanna [0000-0002-1324-7489] Munters, Arielle R. [0000-0003-1512-6565] Pečnerová, Patrícia [0000-0001-9350-1987] Dehasque, Marianne [0000-0002-4640-8306] Ureña, Irene [0000-0001-9724-9977] Ersmark, Erik [0000-0003-4186-7498] Krzewińska, Maja [0000-0002-6702-8724] Rodríguez-Varela, Ricardo [0000-0002-4173-8648] Götherström, Anders [0000-0001-8579-1304] Dalén, Love [0000-0001-6307-8188] Díez-Del-Molino, David [0000-0002-9701-5940] Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics 10 Pág. After over a decade of developments in field collection, laboratory methods and advances in high-throughput sequencing, contamination remains a key issue in ancient DNA research. Currently, human and microbial contaminant DNA still impose challenges on cost-effective sequencing and accurate interpretation of ancient DNA data. Genetic analyses were funded through a grant from the Swedish Research Council (VR grants 2012–3869 and 2017-04647) awarded to L.D.. J.v.S. and L.D. acknowledge support from FORMAS (project 2015–676), T.R.F. acknowledges support from the EU-funded ITN project ArchSci2020 (grant no. 676154) and for the Qimmeq Project funding from the Velux Foundations, the Aage og Johanne Louis-Hansens Fond and the Wellcome Trust (grant no. 210119/Z/18/Z). D.D.d.M. was supported through a Carl Tryggers scholarship (grant CTS 17:109). Open Access funding provided by Stockholm University. Peer reviewed 2023-10-11T11:30:10Z 2023-10-11T11:30:10Z 2020-11-30 artículo http://purl.org/coar/resource_type/c_6501 BMC Genomics 21(1): e844 (2020) http://hdl.handle.net/10261/337042 10.1186/s12864-020-07229-y 1471-2164 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100009244 33256612 2-s2.0-85096938959 https://api.elsevier.com/content/abstract/scopus_id/85096938959 en #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/EC/H2020/676154 Departamento de Reproducción Animal Publisher's version https://doi.org/10.1186/s12864-020-07229-y Sí open application/pdf BioMed Central |
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Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics |
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Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics Feuerborn, Tatiana R. Palkopoulou, Eleftheria van der Valk, Tom von Seth, Johanna Munters, Arielle R. Pečnerová, Patrícia Dehasque, Marianne Ureña, Irene Ersmark, Erik Lagerholm, Vendela Kempe Krzewińska, Maja Rodríguez-Varela, Ricardo Götherström, Anders Dalén, Love Díez-Del-Molino, David Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
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10 Pág. |
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Swedish Research Council |
author_facet |
Swedish Research Council Feuerborn, Tatiana R. Palkopoulou, Eleftheria van der Valk, Tom von Seth, Johanna Munters, Arielle R. Pečnerová, Patrícia Dehasque, Marianne Ureña, Irene Ersmark, Erik Lagerholm, Vendela Kempe Krzewińska, Maja Rodríguez-Varela, Ricardo Götherström, Anders Dalén, Love Díez-Del-Molino, David |
format |
artículo |
topic_facet |
Ancient DNA Competitive mapping DNA contamination removal Palaeogenomics |
author |
Feuerborn, Tatiana R. Palkopoulou, Eleftheria van der Valk, Tom von Seth, Johanna Munters, Arielle R. Pečnerová, Patrícia Dehasque, Marianne Ureña, Irene Ersmark, Erik Lagerholm, Vendela Kempe Krzewińska, Maja Rodríguez-Varela, Ricardo Götherström, Anders Dalén, Love Díez-Del-Molino, David |
author_sort |
Feuerborn, Tatiana R. |
title |
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
title_short |
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
title_full |
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
title_fullStr |
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
title_full_unstemmed |
Competitive mapping allows for the identification and exclusion of human DNA contamination in ancient faunal genomic datasets |
title_sort |
competitive mapping allows for the identification and exclusion of human dna contamination in ancient faunal genomic datasets |
publisher |
BioMed Central |
publishDate |
2020-11-30 |
url |
http://hdl.handle.net/10261/337042 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/501100009244 https://api.elsevier.com/content/abstract/scopus_id/85096938959 |
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1802819791999729664 |