Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop
Among the 57 monoclonal antibodies analyzed within the T-cell group of the Second International Swine CD Workshop, one mAb fell within cluster T14a that included the CD6 standard a38b2 (No. 175). The new mAb MIL8 (No. 082) and a38b2 both precipitated from activated T-cells a 150 kDa monomeric protein. Staining patterns on the various cell types were similar. There was no inhibition of binding of either mAb to peripheral blood T-cells with the opposite mAb. The new mAb, MIL8, reacts with a separate epitope on porcine wCD6.
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Elsevier
1998
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Subjects: | Monoclonal antibodies, T-cells, Porcine wCD6, |
Online Access: | http://hdl.handle.net/20.500.12792/3490 http://hdl.handle.net/10261/294359 |
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dig-inia-es-10261-2943592023-02-20T10:37:57Z Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop Pescovitz, M. D. Book, B. K. Aasted, B. Dominguez, J. Bullido, R. Trebichavsky, I. Novikov, B. Valpotic, I. Nielsen, J. Arn, S. Sachs, D. H. Lunney, J. K. Boyd, P. C. Walker, J. Lee, R. Petrinec, N. Saalmüller, A. Monoclonal antibodies T-cells Porcine wCD6 Among the 57 monoclonal antibodies analyzed within the T-cell group of the Second International Swine CD Workshop, one mAb fell within cluster T14a that included the CD6 standard a38b2 (No. 175). The new mAb MIL8 (No. 082) and a38b2 both precipitated from activated T-cells a 150 kDa monomeric protein. Staining patterns on the various cell types were similar. There was no inhibition of binding of either mAb to peripheral blood T-cells with the opposite mAb. The new mAb, MIL8, reacts with a separate epitope on porcine wCD6. 2023-02-20T10:37:57Z 2023-02-20T10:37:57Z 1998 conference object Veterinary Immunology and Immunopathology 60(3-4): 285-289 (1998) 0165-2427 http://hdl.handle.net/20.500.12792/3490 http://hdl.handle.net/10261/294359 10.1016/S0165-2427(97)00105-0 en none Elsevier |
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Monoclonal antibodies T-cells Porcine wCD6 Monoclonal antibodies T-cells Porcine wCD6 |
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Monoclonal antibodies T-cells Porcine wCD6 Monoclonal antibodies T-cells Porcine wCD6 Pescovitz, M. D. Book, B. K. Aasted, B. Dominguez, J. Bullido, R. Trebichavsky, I. Novikov, B. Valpotic, I. Nielsen, J. Arn, S. Sachs, D. H. Lunney, J. K. Boyd, P. C. Walker, J. Lee, R. Petrinec, N. Saalmüller, A. Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
description |
Among the 57 monoclonal antibodies analyzed within the T-cell group of the Second International Swine CD Workshop, one mAb fell within cluster T14a that included the CD6 standard a38b2 (No. 175). The new mAb MIL8 (No. 082) and a38b2 both precipitated from activated T-cells a 150 kDa monomeric protein. Staining patterns on the various cell types were similar. There was no inhibition of binding of either mAb to peripheral blood T-cells with the opposite mAb. The new mAb, MIL8, reacts with a separate epitope on porcine wCD6. |
format |
conference object |
topic_facet |
Monoclonal antibodies T-cells Porcine wCD6 |
author |
Pescovitz, M. D. Book, B. K. Aasted, B. Dominguez, J. Bullido, R. Trebichavsky, I. Novikov, B. Valpotic, I. Nielsen, J. Arn, S. Sachs, D. H. Lunney, J. K. Boyd, P. C. Walker, J. Lee, R. Petrinec, N. Saalmüller, A. |
author_facet |
Pescovitz, M. D. Book, B. K. Aasted, B. Dominguez, J. Bullido, R. Trebichavsky, I. Novikov, B. Valpotic, I. Nielsen, J. Arn, S. Sachs, D. H. Lunney, J. K. Boyd, P. C. Walker, J. Lee, R. Petrinec, N. Saalmüller, A. |
author_sort |
Pescovitz, M. D. |
title |
Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
title_short |
Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
title_full |
Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
title_fullStr |
Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
title_full_unstemmed |
Analyses of monoclonal antibodies reacting with porcine wCD6 Results from the Second International Swine CD Workshop |
title_sort |
analyses of monoclonal antibodies reacting with porcine wcd6 results from the second international swine cd workshop |
publisher |
Elsevier |
publishDate |
1998 |
url |
http://hdl.handle.net/20.500.12792/3490 http://hdl.handle.net/10261/294359 |
work_keys_str_mv |
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