Non-destructive multibiomarker approach in European quail (Coturnix coturnix coturnix) exposed to the herbicide atrazine

The effect of orally administered atrazine (25 or 100 mg/kg on days 0, 5, and 10 of the experiment) was studied in European quail (Coturnix coturnix coturnix) on four non-destructive biomarkers fecal porphyrins, blood glutathione-S-transferase, glutathione reductase, reduced glutathione, and malondialdehyde (MDA). Uroporphyrin I (UPI) and coproporphyrins I and III (CPIII) were the main porphyrins detected in feces. The lowest dose of ATZ caused a significant (P 〈 0.05) increase in UPI and CPIII at day 5, and the highest dose of ATZ caused an induction of CPI and a significant (P 〈 0.05) decrease in MDA levels at day 30. © Springer Science+Business Media New York 2013.

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Bibliographic Details
Main Authors: de la Casa-Resino, I., Hernández Moreno, David, Navas Antón, José María, Soler, F., Pérez-López, M.
Format: journal article biblioteca
Language:English
Published:  Springer 2013
Online Access:http://hdl.handle.net/20.500.12792/6080
http://hdl.handle.net/10261/294141
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Summary:The effect of orally administered atrazine (25 or 100 mg/kg on days 0, 5, and 10 of the experiment) was studied in European quail (Coturnix coturnix coturnix) on four non-destructive biomarkers fecal porphyrins, blood glutathione-S-transferase, glutathione reductase, reduced glutathione, and malondialdehyde (MDA). Uroporphyrin I (UPI) and coproporphyrins I and III (CPIII) were the main porphyrins detected in feces. The lowest dose of ATZ caused a significant (P 〈 0.05) increase in UPI and CPIII at day 5, and the highest dose of ATZ caused an induction of CPI and a significant (P 〈 0.05) decrease in MDA levels at day 30. © Springer Science+Business Media New York 2013.