Progestogen treatments for cycle management in a sheep model of assisted conception affect the growth patterns, the expression of luteinizing hormone receptors, and the progesterone secretion of induced corpora lutea
Objective To determine, in a sheep model, the effect of a short-term progestative treatment on growth dynamics and functionality of induced corpora lutea. Design Observational, model study. Setting Public university. Patient(s) Sixty adult female sheep. Intervention(s) Synchronization and induction of ovulation with progestogens and prostaglandin analogues; ovarian ultrasonography, blood sampling, and ovariectomy. Main Outcome Measure(s) Determination of pituitary function and morphologic characteristics, expression of luteinizing hormone (LH) receptors, and progesterone secretion of corpora lutea. Result(s) The use of progestative pretreatments for assisted conception affect the growth patterns, the expression of LH receptors, and the progesterone secretion of induced corpora lutea. Conclusion(s): The current study indicates, in a sheep model, the existence of deleterious effects from progestogens on functionality of induced corpora lutea. © 2010 American Society for Reproductive Medicine.
Main Authors: | Letelier, C., García-Fernández, R. A., Contreras-Solis, I., Sanchez, M. A., Garcia-Palencia, P., Sanchez, B., González De Bulnes, Antonio, Flores, J. M. |
---|---|
Format: | journal article biblioteca |
Language: | English |
Published: |
Elsevier
2010
|
Subjects: | Progestogens, Pituitary function, Luteal function, LH receptors, Sheep, |
Online Access: | http://hdl.handle.net/20.500.12792/2371 http://hdl.handle.net/10261/293704 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Molecular cloning of Senegalese sole (Solea senegalensis) follicle-stimulating hormone and luteinizing hormone subunits and expression pattern during spermatogenesis
by: Cerdà, Joan, et al. -
Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance
by: González De Bulnes, Antonio, et al.
Published: (2012) -
Short-term intake of β-carotene-supplemented diets enhances ovarian function and progesterone synthesis in goats
by: Arellano-Rodriguez, G., et al.
Published: (2009) -
The use of different progestin devices in ovarian stimulation protocol affects gene expression in sheep cumulus-oocyte complexes (COC).
by: BRAGANÇA, G. M., et al.
Published: (2018-09-06) -
Long-term suppression of reproductive function by a single dose of gonadotropin-releasing hormone antagonists in a sheep model
by: González De Bulnes, Antonio, et al.
Published: (2006)