Current strategies for subunit and genetic viral veterinary vaccine development

Developing vaccines for livestock provides researchers with the opportunity to perform efficacy testing in the natural hosts. This enables the evaluation of different strategies, including definition of effective antigens or antigen combinations, and improvement in delivery systems for target antigens so that protective immune responses can be modulated or potentiated. An impressive amount of knowledge has been generated in recent years on vaccine strategies and consequently a wide variety of antigen delivery systems is now available for vaccine research. This paper reviews several antigen production and delivery strategies other than those based on the use of live viral vectors. Genetic and protein subunit vaccines as well as alternative production systems are considered in this review. © 2011 Elsevier B.V.

Bibliographic Details

Main Authors:	Brun Torres, Alejandro, Barcena Del Riego, Juan Ángelo, Blanco Lavilla, Esther, Borrego, B., Dory, D., Escribano, J. M., Le Gall-Reculé, G., Ortego, J., Dixon, L. K.
Format:	artículo de revisión biblioteca
Language:	English
Published:	Elsevier 2011
Subjects:	Veterinary vaccines, DNA vaccines, Subunit vaccines,
Online Access:	http://hdl.handle.net/20.500.12792/4630 http://hdl.handle.net/10261/291392
Tags:	Add Tag No Tags, Be the first to tag this record!