Consequences of in vitro culture conditions on embryo development and quality
Despite major efforts directed at improving the yield of blastocysts from immature oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts produced in vivo. These differences are manifested at the level of morphology, metabolism, gene expression and cryotolerance, and may have a knock-on effect further along the developmental axis. Evidence suggesting that in vitro culture conditions, while capable of producing blastocysts in relatively high numbers, are far from optimal with deficiencies being manifested in terms of abnormally large offspring. It is clear nowadays that modification of the post-fertilization culture environment in vitro can improve blastocyst quality to some extent. © 2008 The Authors.
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2008
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dig-inia-es-10261-2898242023-02-17T08:24:17Z Consequences of in vitro culture conditions on embryo development and quality Rizos Dimitrios, Dimitrios Clemente, M. Bermejo Álvarez, Pablo De La Fuente, J. Lonergan, P. Gutiérrez Adán, Alfonso Despite major efforts directed at improving the yield of blastocysts from immature oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts produced in vivo. These differences are manifested at the level of morphology, metabolism, gene expression and cryotolerance, and may have a knock-on effect further along the developmental axis. Evidence suggesting that in vitro culture conditions, while capable of producing blastocysts in relatively high numbers, are far from optimal with deficiencies being manifested in terms of abnormally large offspring. It is clear nowadays that modification of the post-fertilization culture environment in vitro can improve blastocyst quality to some extent. © 2008 The Authors. 2023-02-17T08:24:17Z 2023-02-17T08:24:17Z 2008 artículo de revisión Reproduction in Domestic Animals 43(4): 44-50 (2008) 0936-6768 http://hdl.handle.net/20.500.12792/5418 http://hdl.handle.net/10261/289824 10.1111/j.1439-0531.2008.01230.x 1439-0531 en none Wiley |
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Despite major efforts directed at improving the yield of blastocysts from immature oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts produced in vivo. These differences are manifested at the level of morphology, metabolism, gene expression and cryotolerance, and may have a knock-on effect further along the developmental axis. Evidence suggesting that in vitro culture conditions, while capable of producing blastocysts in relatively high numbers, are far from optimal with deficiencies being manifested in terms of abnormally large offspring. It is clear nowadays that modification of the post-fertilization culture environment in vitro can improve blastocyst quality to some extent. © 2008 The Authors. |
format |
artículo de revisión |
author |
Rizos Dimitrios, Dimitrios Clemente, M. Bermejo Álvarez, Pablo De La Fuente, J. Lonergan, P. Gutiérrez Adán, Alfonso |
spellingShingle |
Rizos Dimitrios, Dimitrios Clemente, M. Bermejo Álvarez, Pablo De La Fuente, J. Lonergan, P. Gutiérrez Adán, Alfonso Consequences of in vitro culture conditions on embryo development and quality |
author_facet |
Rizos Dimitrios, Dimitrios Clemente, M. Bermejo Álvarez, Pablo De La Fuente, J. Lonergan, P. Gutiérrez Adán, Alfonso |
author_sort |
Rizos Dimitrios, Dimitrios |
title |
Consequences of in vitro culture conditions on embryo development and quality |
title_short |
Consequences of in vitro culture conditions on embryo development and quality |
title_full |
Consequences of in vitro culture conditions on embryo development and quality |
title_fullStr |
Consequences of in vitro culture conditions on embryo development and quality |
title_full_unstemmed |
Consequences of in vitro culture conditions on embryo development and quality |
title_sort |
consequences of in vitro culture conditions on embryo development and quality |
publisher |
Wiley |
publishDate |
2008 |
url |
http://hdl.handle.net/20.500.12792/5418 http://hdl.handle.net/10261/289824 |
work_keys_str_mv |
AT rizosdimitriosdimitrios consequencesofinvitrocultureconditionsonembryodevelopmentandquality AT clementem consequencesofinvitrocultureconditionsonembryodevelopmentandquality AT bermejoalvarezpablo consequencesofinvitrocultureconditionsonembryodevelopmentandquality AT delafuentej consequencesofinvitrocultureconditionsonembryodevelopmentandquality AT lonerganp consequencesofinvitrocultureconditionsonembryodevelopmentandquality AT gutierrezadanalfonso consequencesofinvitrocultureconditionsonembryodevelopmentandquality |
_version_ |
1767603010227142656 |