Differential neurovirulence of Usutu virus lineages in mice and neuronal cells
22 Pág. Departamento de Biotecnología
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BioMed Central
2021-01-06
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Subjects: | Arbovirus, Central nervous system, Flavivirus, Neurotropism, Usutu virus, |
Online Access: | http://hdl.handle.net/10261/283266 http://dx.doi.org/10.13039/501100008222 http://dx.doi.org/10.13039/501100001665 https://api.elsevier.com/content/abstract/scopus_id/85098766066 |
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dig-inia-es-10261-2832662024-10-27T21:46:04Z Differential neurovirulence of Usutu virus lineages in mice and neuronal cells Clé, Marion Constant, Orianne Barthelemy, Jonathan Desmetz, Caroline Martin, Marie France Lapeyre, Lina Cadar, Daniel Savini, Giovanni Teodori, Liana Monaco, Federica Schmidt-Chanasit, Jonas Saiz Calahorra, Juan Carlos Gonzales, Gaëlle Lecollinet, Sylvie Beck, Cécile Gosselet, Fabien Van de Perre, Philippe Foulongne, Vincent Salinas, Sara Simonin, Yannick Université de Montpellier Agence Nationale de la Recherche (France) Constant, Orianne [0000-0003-4141-5563] Barthelemy, Jonathan [0000-0003-3292-4032] Desmetz, Caroline [0000-0002-8530-6011] Martin, Marie France [0000-0003-3165-0375] Lapeyre, Lina [0000-0003-4782-1386] Cadar, Daniel [0000-0002-8063-2766] Savini, Giovanni [0000-0001-7933-7367] Teodori, Liana [0000-0001-5533-0099] Schmidt-Chanasit, Jonas [0000-0003-4433-0231] Saiz Calahorra, Juan Carlos [0000-0001-8269-5544] Lecollinet, Sylvie [0000-0001-8535-2133] Beck, Cécile [0000-0002-9053-1416] Gosselet, Fabien [0000-0002-0481-5026] Van de Perre, Philippe [0000-0002-3912-0427] Foulongne, Vincent [0000-0003-3741-754X] Salinas, Sara [0000-0003-4492-2093] Simonin, Yannick [0000-0002-3475-1369] Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus 22 Pág. Departamento de Biotecnología Usutu virus (USUV) is an emerging neurotropic arthropod-borne virus recently involved in massive die offs of wild birds predominantly reported in Europe. Although primarily asymptomatic or presenting mild clinical signs, humans infected by USUV can develop neuroinvasive pathologies (including encephalitis and meningoencephalitis). Similar to other flaviviruses, such as West Nile virus, USUV is capable of reaching the central nervous system. However, the neuropathogenesis of USUV is still poorly understood, and the virulence of the specific USUV lineages is currently unknown. One of the major complexities of the study of USUV pathogenesis is the presence of a great diversity of lineages circulating at the same time and in the same location. This work was funded by REACTing (reference: YY/FC/2018-032) and Montpellier University of Excellence (MUSE) through ANR (the French National Research Agency) with the reference ANR-16-IDEX-0006 and the Labex EpiGenMed “Investissements d’avenir”, program “ANR-10-LABX-12-01.” Peer reviewed 2022-11-18T11:31:52Z 2022-11-18T11:31:52Z 2021-01-06 artículo http://purl.org/coar/resource_type/c_6501 Journal of Neuroinflammation 18(1): 11 (2021) 1742-2094 http://hdl.handle.net/10261/283266 10.1186/s12974-020-02060-4 http://dx.doi.org/10.13039/501100008222 http://dx.doi.org/10.13039/501100001665 33407600 2-s2.0-85098766066 https://api.elsevier.com/content/abstract/scopus_id/85098766066 en Journal of neuroinflammation Publisher's version https://doi.org/10.1186/s12974-020-02060-4 Sí open BioMed Central |
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Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus |
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Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus Clé, Marion Constant, Orianne Barthelemy, Jonathan Desmetz, Caroline Martin, Marie France Lapeyre, Lina Cadar, Daniel Savini, Giovanni Teodori, Liana Monaco, Federica Schmidt-Chanasit, Jonas Saiz Calahorra, Juan Carlos Gonzales, Gaëlle Lecollinet, Sylvie Beck, Cécile Gosselet, Fabien Van de Perre, Philippe Foulongne, Vincent Salinas, Sara Simonin, Yannick Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
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22 Pág.
Departamento de Biotecnología |
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Université de Montpellier |
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Université de Montpellier Clé, Marion Constant, Orianne Barthelemy, Jonathan Desmetz, Caroline Martin, Marie France Lapeyre, Lina Cadar, Daniel Savini, Giovanni Teodori, Liana Monaco, Federica Schmidt-Chanasit, Jonas Saiz Calahorra, Juan Carlos Gonzales, Gaëlle Lecollinet, Sylvie Beck, Cécile Gosselet, Fabien Van de Perre, Philippe Foulongne, Vincent Salinas, Sara Simonin, Yannick |
format |
artículo |
topic_facet |
Arbovirus Central nervous system Flavivirus Neurotropism Usutu virus |
author |
Clé, Marion Constant, Orianne Barthelemy, Jonathan Desmetz, Caroline Martin, Marie France Lapeyre, Lina Cadar, Daniel Savini, Giovanni Teodori, Liana Monaco, Federica Schmidt-Chanasit, Jonas Saiz Calahorra, Juan Carlos Gonzales, Gaëlle Lecollinet, Sylvie Beck, Cécile Gosselet, Fabien Van de Perre, Philippe Foulongne, Vincent Salinas, Sara Simonin, Yannick |
author_sort |
Clé, Marion |
title |
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
title_short |
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
title_full |
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
title_fullStr |
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
title_full_unstemmed |
Differential neurovirulence of Usutu virus lineages in mice and neuronal cells |
title_sort |
differential neurovirulence of usutu virus lineages in mice and neuronal cells |
publisher |
BioMed Central |
publishDate |
2021-01-06 |
url |
http://hdl.handle.net/10261/283266 http://dx.doi.org/10.13039/501100008222 http://dx.doi.org/10.13039/501100001665 https://api.elsevier.com/content/abstract/scopus_id/85098766066 |
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1816136168244248576 |