The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques
5 páginas, 2 tablas.
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | artículo biblioteca |
| Language: | English |
| Published: |
Elsevier
2013-06
|
| Subjects: | Sheep, Gastrointestinal nematodes, Anthelmintic resistance, Faecal Egg Count Reduction Test, Egg Hatch Assay, Larval Feeding Inhibition Assay, |
| Online Access: | http://hdl.handle.net/10261/80959 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/100007652 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
dig-igm-es-10261-80959 |
|---|---|
| record_format |
koha |
| spelling |
dig-igm-es-10261-809592021-04-13T15:13:24Z The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques Martínez Valladares, María Martínez Pérez, José Manuel Robles Pérez, D. Cordero Pérez, Coral Famularo, M. R. Fernández Pato, N. Castañón Ordóñez, Luciano Rojo Vázquez, Francisco Antonio Ministerio de Educación y Ciencia (España) CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) Consejo Superior de Investigaciones Científicas (España) European Commission Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay 5 páginas, 2 tablas. The aim of this study was to update the anthelmintic resistance (AR) status in sheep flocks infected by gastrointestinal nematodes (GIN) by means of in vivo and in vitro methods in the northwest of Spain. With this objective, we studied the efficacy of benzimidazoles (BZs), imidazothiazoles (IMs) and macrocyclic lactones (MLs), between 2006 and 2011. The sampling area was the Autonomous Community of Castilla y Leon but the majority of the flocks were located in the province of Leon. When the mean of GIN eggs per gram (epg) in faeces in a flock was higher than 150, the in vivo Faecal Egg Count Reduction Test (FECRT) was carried out. According to this test, AR was present in 63.6% of flocks, independently of the anthelmintic used. Flocks were mainly resistant to levamisole (LEV) (59.0%), followed by ivermectin (IVM) (27.3%) and albendazole (13.6%). Multidrug-resistance was also observed in 27.2% of the flocks, one of them being resistant to all anthelmintic families, including long-acting moxidectin. Comparing the evolution of AR in the last decade, between 1999 and 2011, the level of resistance to BZs and MLs was fairly constant throughout the time by means of the FECRT. However, the resistance to LEV increased significantly in only one decade since during the period 1999-2003 the percentage was 38.5%. The AR status was also measured by in vitro techniques in those flocks with an egg output lower than 150 epg. The prevalence of AR to BZs reached the 35.3% by Egg Hatch Assay. However, the level of resistance reported for LEV and IVM was 61.5% and 23.5%, respectively, by using the Larval Feeding Inhibition Assay, percentages very similar to those reported with the FECRT. national projects INIA-MEC RTA2006-00183-C03-02 RTA2010-00094-C03-02; Consejo Superior de Investigaciones Cientificas (CSIC); European Social Fund Peer reviewed 2013-08-23T10:04:06Z 2013-08-23T10:04:06Z 2013-06 artículo http://purl.org/coar/resource_type/c_6501 Veterinary Parasitology, 191 (1-2) : 177-181 (2013) 0304-4017 http://hdl.handle.net/10261/80959 10.1016/j.vetpar.2012.08.009 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/100007652 en http://dx.doi.org/10.1016/j.vetpar.2012.08.009 open Elsevier |
| institution |
IGM ES |
| collection |
DSpace |
| country |
España |
| countrycode |
ES |
| component |
Bibliográfico |
| access |
En linea |
| databasecode |
dig-igm-es |
| tag |
biblioteca |
| region |
Europa del Sur |
| libraryname |
Biblioteca del IGM España |
| language |
English |
| topic |
Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay |
| spellingShingle |
Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay Martínez Valladares, María Martínez Pérez, José Manuel Robles Pérez, D. Cordero Pérez, Coral Famularo, M. R. Fernández Pato, N. Castañón Ordóñez, Luciano Rojo Vázquez, Francisco Antonio The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| description |
5 páginas, 2 tablas. |
| author2 |
Ministerio de Educación y Ciencia (España) |
| author_facet |
Ministerio de Educación y Ciencia (España) Martínez Valladares, María Martínez Pérez, José Manuel Robles Pérez, D. Cordero Pérez, Coral Famularo, M. R. Fernández Pato, N. Castañón Ordóñez, Luciano Rojo Vázquez, Francisco Antonio |
| format |
artículo |
| topic_facet |
Sheep Gastrointestinal nematodes Anthelmintic resistance Faecal Egg Count Reduction Test Egg Hatch Assay Larval Feeding Inhibition Assay |
| author |
Martínez Valladares, María Martínez Pérez, José Manuel Robles Pérez, D. Cordero Pérez, Coral Famularo, M. R. Fernández Pato, N. Castañón Ordóñez, Luciano Rojo Vázquez, Francisco Antonio |
| author_sort |
Martínez Valladares, María |
| title |
The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| title_short |
The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| title_full |
The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| title_fullStr |
The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| title_full_unstemmed |
The present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of Spain by in vivo and in vitro techniques |
| title_sort |
present status of anthelmintic resistance in gastrointestinal nematode infections of sheep in the northwest of spain by in vivo and in vitro techniques |
| publisher |
Elsevier |
| publishDate |
2013-06 |
| url |
http://hdl.handle.net/10261/80959 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100000780 http://dx.doi.org/10.13039/100007652 |
| work_keys_str_mv |
AT martinezvalladaresmaria thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT martinezperezjosemanuel thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT roblesperezd thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT corderoperezcoral thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT famularomr thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT fernandezpaton thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT castanonordonezluciano thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT rojovazquezfranciscoantonio thepresentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT martinezvalladaresmaria presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT martinezperezjosemanuel presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT roblesperezd presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT corderoperezcoral presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT famularomr presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT fernandezpaton presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT castanonordonezluciano presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques AT rojovazquezfranciscoantonio presentstatusofanthelminticresistanceingastrointestinalnematodeinfectionsofsheepinthenorthwestofspainbyinvivoandinvitrotechniques |
| _version_ |
1777663938369945600 |